Analysis of Biological Therapy of Psoriasis in Faculty Hospital Hradec Králové in 2006–2011


Authors: J. Ettler 1,2;  K. Ettler 1
Authors‘ workplace: Klinika nemocí kožních a pohlavních FN a LF UK Hradec Králové přednosta doc. MUDr. Karel Ettler, CSc. 1;  Dermatovenerologická klinika 2. LF UK a FN Královské Vinohrady, Praha přednosta prof. MUDr. Petr Arenberger, DrSc., MBA 2
Published in: Čes-slov Derm, 89, 2014, No. 3, p. 128-132
Category: Clinical and laboratory Research

Overview

Biological therapy of psoriasis is modern, expensive and highly effective therapeutical modality for this chronic disease. Currently, there are 4 biologics registered for the treatment of severe psoriasis in the Czech Republic: etanercept, adalimumab, infliximab and ustekinumab. Retrospective analysis performed in the Faculty Hospital Hradec Králové in the period 2006–2011 did not show statistically significant difference of efficacy among biologics used after the first three months of therapy. The main reason for therapy discontinuation was loss of efficacy (57,3 %). No complications and side effects were recorded in 54,8 % of patients.

Key words:
biological therapy of psoriasis – efficacy – side effects


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Labels
Dermatology & STDs Paediatric dermatology & STDs
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