The possibility of using progesterone receptor modulators in the treatment of myomas


Authors: O. Šimetka;  J. Klát;  S. Bajsová
Authors‘ workplace: Gynekologicko-porodnická klinika FN, Ostrava, přednosta doc. MUDr. O. Šimetka, Ph. D., MBA
Published in: Čes. Gynek.2016, 81, č. 6 s. 452-457

Overview

Objective:
To summarize the knowledge about the effect of selective progesterone receptor modulators and their use in the treatment of myomas in women of childbearing age and in perimenopause.

Design:
Review article.

Results:
Long-term treatment with ulipristal acetate maximizes its effectiveness, it helps to achieve faster bleeding control and increases the number of pa­tients with fibroid volume reduction of more than 50%. Ulipristal acetate is the most effective drug in the medical treatment of myomas and its use will change the approach to surgical treatment.

Keywords:
myomas, medical therapy, surgical therapy, selective progesteron receptor modulators, ulipristal acetate


Sources

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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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