Pregnancy in women with congenital bleeding disorder


Authors: T. Binder 1;  P. Salaj 2;  V. Komrska 3
Authors‘ workplace: Gynekologicko-porodnická klinika FZS UJEP a MN, Ústí nad Labem, přednosta doc. MUDr. T. Binder, CSc. 1;  ÚHKT, Praha, přednosta prof. MUDr. P. Cetkovský, Ph. D., MBA 2;  Dětská hemato-onkologická klinika 2. LF UK a FN Motol, Praha, přednosta prof. MUDr. J. Starý, DrSc. 3
Published in: Čes. Gynek.2016, 81, č. 6 s. 420-425

Overview

The aim of the study:
To highlight the risks associated with pregnancy at women with von Willebrand´s disease or hemophilia. Introduce the rules of multidisciplinary prenatal and peripartal care to minimalize these risks. The article is accompanied by case report where maladministration led to fatal consequences for the newborn.

Design:
Review and case report.

Seatings:
Department Obstetric and Gynecology UJEP and Masaryk´s Hospital Ústí n/Labem, Institute Haematology and Blood Transfer Prague, Children´s Haemato-onkology Clinic University Hospital Prague Motol.

Coclusions:
The pregnancy in both above-mentioned diseases is risky. The close multidisciplinary collaboration is required.

Keywords:
pregnancy, von Willebrad´s disease, hemophilia


Sources

1. Dunkley, SM., Russell, SJ., Rowell, JA., et al. A consensus statement on the management of pregnancy and delivery in women who are carriers of or have bleeding disorders. Med J Aust, 2009, 19, 191(8), p. 460–463.

2. Huq, FY., Kadir, RA. Management of pregnancy, labour and delivery in women with inherited bleeding disorders. Haemophilia, 201, 17, Suppl. 1, p. 20–30.

3. Chee, YL., Townend, J., Crowther, M., et al. Assessment of von Willebrand disease as a risk factor for primary postpartum haemorrhage. Haemophilia, 2012, 18, p. 593–597.

4. James, AH., Jamison, MG. Bleeding events and other complications during pregnancy and childbirth in women with von Willebrand disease. J Thromb Haemost, 2007, 5(6), p. 1165–1169.

5. Kadir, RA., Lee, CA., Sabin, CA., et al. Pregnancy in women with von Willebrand‘s disease or factor XI deficiency. Br J Obstet Gynaecol, 1998, 105(3), p. 314–321.

6. Kujovich, JL. von Willebrand disease and pregnancy. J Thromb Haemost, 2005, 3(2), p. 246–53. Review.

7. Lee, C., Kessler, C., Makris, M., Gough, S. Hemophylia, 2011, 17(1), p. 1365–2516.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account