Authors: L. Saksun 1; A. Ostró 1; M. Wágnerová 2 Authors‘ workplace: II. gynekologicko-pôrodnická klinika LF UPJŠ a FN L. Pasteura, Košice, prednosta doc. MUDr. A. Ostró, CSc. 2Klinika rádioterapie a onkológie LF UPJŠ a FN L. Pasteura, Košice, prednosta MUDr. I. Andrašina, CSc. 1 Published in: Ceska Gynekol 2002; (5): 275-277 Category:
Objective: One of the most important factors contributing to developing of the breast cancer isa female organism exposure to estrogens. Thickness and structure of endometrium in postmenopausalwomen is a sign of the hormonal status. The goal of the study was to investigate whetherthere is a difference in the endometrial thickness and quality in postmenopausal women withbreast cancer.Design: Prospective cohort study.Setting: Ultrasound Unit, 2nd Department of Obstetrics and Gynecology, Medical School andMedical Teaching Hospital of L. Pasteur, Košice, Slovakia.Material and Methods: Endometrial thickness was measured by transvaginal ultrasonography in21 patients with histologically verified breast cancer and was compared with a group of 26 wellwomen. We assessed the thickness of endometrium, the size of uterus and the endometrium/myometriumindex.Results: Despite the fact there existed a difference between these two groups (the average thicknessof 3.6 mm and 2.9 mm), the result was not statistically applicable to show a correlation witha benign or malignant breast tissue.Conclusion: The results may support the theory of breast cancerogenesis in correlation withestrogen influence or increased incidence of estrogen receptors, respectively. As definitive statisticalresult can not be stated due to a limited group of patients, more investigation might benecessary in the future. The study dealing with a similar problem was not found in availablepublications.
Key words: endometrium, breast cancer, ultrasonography
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