Authors: J. Jeníček 1; Tomáš Fait 1; A. Jedličková 2; J. Živný 1 Authors‘ workplace: Gynek. -porod. klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. J. Živný, DrSc. 2 Ústav pro lékařskou mikrobiologii 1. LF UK a VFN, Praha, přednosta doc. MUDr. A. Souček, CSc. 1 Published in: Ceska Gynekol 1999; (5): 313-316 Category:
Objective: To verify the significance of Cefazolin administration to women who were indicated forcaesarean section.Setting: Department of Obstetrics and Gynecology, First Faculty of Medicine, Prague, Czechrepublic.Methods: Cefazolin was administered to 30 women with a patient history risk in a dose of 1 mg i.v.after ligation of the umbilical cord. The control group consisted of 30 women. Observed parame-ters: weight gain during pregnancy, indications for caesarean section, culture from the cervix andvagina prior to the caesarean section, culture from the amniotic fluid, culture from the 4 th daylochia, temperature curve, leucocyte count before and 4 days after the operation, complicationsafter the surgery, administration of antibiotics, and length of hospitalisation.Results: In the group with antibiotic prophylaxis, we observed a more favourable course of thetemperature curve and a smaller leucocyte count the fourth day after the surgery (p < 0.01), incomparison with the women without prophylaxis. The duration of hospitalisation in women withantibiotic prophylaxis was one day shorter and there was no occurence of febrile complicationsrequiring further antibiotic treatment.Conclusion: Cafazolin is advantageous antibiotic for prophylaxis in caesarean section in patientswith risk.
Key words: prophylaxis, caesarean section, Cefazolin
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