Isotachophoretic Analysis of Ophthalmic Drops

Czech version

Authors: I. Valášková; R. Adamčová; B. Boháčová; E. Havránek
Authors‘ workplace: Katedra farmaceutickej analýzy a nukleárnej farmácie Farmaceutickej fakulty UniverzityKomenského, Bratislava
Published in: Čes. slov. Farm., 1999; , 179-182
Category:

Overview

The method of capillary isotachophoresis was employed to analyse the active ingredients in theophthalmic drops Tetrakain 0.5% and Atropin 1%. A method has been worked out which representssimplification and increases selectivity in comparison with titration determination according PhBs 4.The pre-adjustment of samples only consists in necessary dilution with demineralised water, thelength of determination not exceeding ten minutes. The method was applied to the investigation ofstability of eye drops.

Key words:
tetracainium chloride – atropinium sulfate – ophthalmic drops –capillary isotachophoresis

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Article was published in

Czech and Slovak Pharmacy

1999 Issue 4