Advances in the Development of New Antituberculotics of the Group of Five-MemberedHeterocyclic Compounds Containing One Species of the Heteroatom

Czech version

Authors: K. Waisser; L. Drhová
Authors‘ workplace: Katedra anorganické a organické chemie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové
Published in: Čes. slov. Farm., 1999; , 147-155
Category:

Overview

Tuberculosis and other mycobacterial diseases are considered at present to be one of the prominentproblems of health services. Since 1985, and in particular in the 1990s, a search for new structuresof antimycobacterial drugs is one of the first and foremost fields of chemotherapeutic research. Thepresent review paper surveys the studies carried out in the field of five-membered heterocycliccompounds containing one species of the heteroatom (furan, thiophene, pyrrol, diazoles, triazoles,tetrazoles, indol, carbazol, and other more complex cyclic compounds of nitrogen and sulfur) since1984, making use of the journal Chemical Abstracts and original papers.

Key words:
tuberulostatics – five-membered heterocycles – mycobacteria

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Article was published in

Czech and Slovak Pharmacy

1999 Issue 4