Authors: M. Blešová; J. Csöllei; P. Novomeský 1; R. Opatřilová Authors‘ workplace: Ústav chemických léčiv Farmaceutické fakulty Veterinární a farmaceutické univerzity, Brno 1 Katedra farmaceutickej analýzy a nukleárnej farmácie Farmaceutickej fakulty UniverzityKomenského, Bratislava Published in: Čes. slov. Farm., 1999; , 94-96 Category:
The paper presents some procedures of the analytical evaluation of a newly prepared substance withbeta-adrenolytic activity. The substance was characterised by its melting point, solubility; theexperimental partition coefficient, dissociation constant, surface activity were determined. Theprocedures for identification, purity evaluation and determination of the content of the activeprinciple ( 1 H-NMR, 13 C-NMR, IR, UV spectra, thin-layer chromatography, acidimetric determina-tion in a non-aqueous medium, extraction titration in a heterogeneous medium, extraction-photo-metric determination) were elaborated.
Key words: N-isopropyl-3-[2-acetyl-4-(propoxycarbonylamino)phenoxy]-2-hydroxypropyl-ammonium chloride – identification – purity detection – content determination
Don‘t have an account? Create new account
Enter the email address that you registered with. We will send you instructions on how to set a new password.
