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Sense of smell examination before and after surgery for nasal polyposis


Authors: P. Fundová 1;  O. Vorobiov 1;  J. Holubová 1;  L. Svobodová 1;  J. Astl 1;  T. Belšan 2;  M. Májovský 3;  V. Masopust 3;  D. Netuka 3
Authors‘ workplace: Klinika otorhinolaryngologie a maxilofaciální, chirurgie 3. LF UK a ÚVN, Praha 1;  Radiodiagnostické oddělení ÚVN, Praha 2;  Neurochirugická a neuroonkologická, klinika 1. LF UK a ÚVN, Praha 3
Published in: Cesk Slov Neurol N 2019; 82(4): 396-400
Category: Original Paper
doi: https://doi.org/10.14735/amcsnn2019396

Overview

Aim: To verify improvement of olfactory function in patients with chronic rhinosinusitis with nasal polyps and concurrent sense of smell deterioration after functional endoscopic sinus surgery.

Materials and methods: This study included patients who underwent functional endoscopic sinus surgery, either pansinus surgery, supraturbinal antrostomy (STA) and anterior ethmoidectomy or limited STA in a study period from 2013 to 2016. Sniffin Sticks test was applied to study the sense of smell before surgery and during follow up 3, 6 and 12 months after surgery.

Results: Cohort consisted of 257 patients. Altogether, pansinus surgery was performed in 181 cases, STA and anterior ethmoidectomy in 49 cases and only limited STA in 27 cases. The sense of smell was improved one year after the surgery, when we assume a stabilized and final state, as follows: in the first group it was 59.6%, in the second it was 55.1% and in the third it was 29.6% of patients.

Conclusions: In our cohort, the best results were observed in cases of primary pansinus surgery in patients who suffered preoperative anosmia. The improvement of sense of smell, in some cases even normalization of sense of smell, improved the quality of life of patients including even their safety.

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.


鼻息肉手术前后的嗅觉检查

目的:探讨鼻内镜鼻窦手术后鼻息肉合并慢性鼻-鼻窦炎患者嗅觉功能的改善。


材料和方法:本研究包括2013年至2016年研究期间接受功能性内窥镜鼻窦手术、全鼻窦手术、膀胱上腔窦造口术(STA)和前筛窦切除术或有限的STA的患者。术前、术后3个月、6个月、12个月分别用嗅液棒试验研究患者的嗅觉。


结果:队列包括257例患者。共有181例接受了全鼻窦手术,49例接受了STA和筛前切除术,仅27例接受了有限的STA。术后一年嗅觉得到改善,假设是稳定的最终状态,如下:第一组为59.6%,第二组为55.1%,第三组为29.6%。


结论:在我们的队列中,最好的结果出现在术前出现嗅觉缺失的患者的原发全鼻窦手术中。嗅觉的改善,在某些情况下甚至是嗅觉的正常化,改善了病人的生活质量,甚至包括他们的安全。


关键字:慢性鼻-鼻窦炎–鼻息肉–气味–功能性内窥镜鼻窦手术– Lund-Mackay CT评分–鼻窦CT –失眠–失眠

Keywords:

chronic rhinosinusitis – nasal polyps – smell – functional endoscopic sinus surgery – Lund-Mackay CT score – nasal sinuses CT – hyposmia – anosmia


Sources

1. Schofield PW, Moore TM, Gardner A. Traumatic brain injury and olfaction: a systematic review. Front Neurol 2014; 5: 5. doi: 10.3389/ fneur.2014.00005.

2. Frank ME, Hettinger TP. Tracking traumatic head injuries with the chemical senses. World J Otorhinolaryngol Head Neck Surg 2018; 4(1): 46–49. doi: 10.1016/ j.wjorl.2018.02.007.

3. Kim SW, Park B, Lee TG et al. Olfactory dysfunction in nasal bone fracture. Arch Craniofac Surg 2017; 18(2):
92–96.

4. Sigurdardottir S, Jerstad T, Andelic N et al. Olfactory dysfunction, gambling task performance and intracranial lesions after traumatic brain injury. Neuropsycholo­-
gy 2010; 24(4): 504–513. doi: 1310.1037/ a0018934.

5. Magerová H, Vyhnálek M, Laczó J et al. Přínos vyšetření čichu v časné dia­gnostice demencí neurodegenerativní etiologie. Cesk Slov Neurol N 2008; 71/ 104(3): 298–302.

6. Martončíková M, Orendáčová J, Račeková E. Klinický význam testovania čuchových funkcií pre včasné odhalenie neurodegeneratívnych ochorení. Cesk Slov Neurol N 2003; 66/ 99(1): 3–7.

7. Radil T, Roth J, Tichý J et al. Porucha čichu: příznak Parkinsonovy nemoci? Cesk Slov Neurol N 1995; 58/ 91(6): 286–289.

8. Vodička J, Pecková L, Kopal A et al. Vyšetření čichu u neurologických onemocnění pomocí Testu parfémovaných fixů. Cesk Slov Neurol N 2010; 73/ 106(1): 45–50.

9. DeVere R. Disorders of taste and smell. Continuum (Minneap Minn) 2017; 23(2): 421–446. doi: 10.1212/ CON. 0000000000000463.

10. Silva MM, Mercer PB, Witt MC et al. Olfactory dysfunction in Alzheimer‘s disease Systematic review and meta-analysis. Dement Neuropsychol 2018; 12(2):
123–132. doi: 10.1590/ 1980-57642018dn12-020004.

11. Martinec Nováková L, Štěpánková H, Vodička J et al. Přínos vyšetření čichu pro dia­gnostiku neurodegene­rativních onemocnění. Cesk Slov Neurol N 2015; 78(5):
517–525.

12. Vyhnálek M, Magerová H, Andel R et al. Olfactory identification in amnestic and non-amnestic mild cognitive impairment and its neuropsychological correlates. J Neurol Sci 2015; 349(1–2): 179–184. doi: 10.1016/ j.jns.2015.01.014.

13. Magerová H, Vyhnálek M, Laczó J et al. Odor identification in frontotemporal lobar degeneration subtypes. Am J Alzheimers Dis Other Demen 2014; 29(8): 762–768. doi: 10.1177/ 1533317514539033.

14. Proskynitopoulos PJ, Stippler M, Kasper EM. Post-traumatic anosmia in patients with mild traumatic brain injury (mTBI): a systematic and illustrated review. Surg Neurol Int 2016; 7 (Suppl 10): S263–S275. doi: 10.4103/ 2152-7806.181981.

15. Dedeciusová M, Májovský M, Fundová P et al. Olfaktoriální meningiomy – chirurgická léčba, její rizika a možnosti zachování čichu. Cesk Slov Neurol N 2018; 81/ 114(1): 11–16. doi: 10.14735/ amcsnn201811.

16. Kohli P, Naik AN, Harruff EE et al. The Prevalence of olfactory dysfunction in chronic rhinosinusitis. Laryngoscope 2017; 127(2): 309–320. doi: 10.1002/ lary.26
316.

17. Hauser LJ, Chandra RK, Li P et al. Role of tissue eosinophils in chronic rhinosinusitis-associated olfactory loss. Int Forum Allergy Rhinol 2017; 7(10): 957–962. doi: 10.1002/ alr.21994.

18. Thompson CF, Kern RC, Conley DB. Olfaction in endoscopic sinus and skull base surgery. Otolaryngol Clin North Am 2015; 48(5): 795–804. doi: 10.1016/ j.otc.2015.05.007.

19. Schubert CR, Fischer ME, Pinto AA et al. Sensory Impairments and risk of mortality in older adults. J Gerontol A Biol Sci Med Sci 2016; 72(5): 710–715. doi: 10.1093/ gerona/ glw036.

20. Wang L, Walker VE, Sardi H et al. The correlation between physiological and psychological responses to odour stimulation in human subjects. Clin Neurophysiol 2002; 113(4): 542–551.

21. Håkansson K, Bachert C, Konge L et al. Airway inflammation in chronic rhinosinusitis with nasal polyps and asthma: the united airways concept further supported. PLoS One 2015; 10(7): e0127228. doi: 10.1371/ journal.pone.0127228.

22. Fokkens WJ, Lund VJ, Mullol J et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 2012; 50(1): 1–12. doi: 10.4193/ Rhino50E2.

23. Bonfils P. Evaluation of the combined medical and surgical treatment in nasal polyposis. I: functional results. Acta Otolaryngol 2007; 127(4): 436–446. doi: 10.1080/ 00016480600895078.

24. Hsu CY, Wang YP, Shen PH et al. Objective olfactory outcomes after revision endoscopic sinus surgery. Am J Rhinol Allergy 2013; 27(4): e96–e100. doi: 10.2500/ ajra.2013.27.3939.

25. Litvack JR, Mace J, Smith TL. Does olfactory function improve after endoscopic sinus surgery? Otolaryngol Head Neck Surg 2009; 140(3): 312–319. doi: 10.1016/ j.otohns.2008.12.006.

26. Rudmik L, Smith TL. Olfactory improvement after endoscopic sinus surgery. Curr Opin Otolaryngol
Head Neck Surg 2012; 20(1): 29–32. doi: 10.1097/ MOO. 0b013e32834dfb3d.

27. Hummel T, Sekinger B, Wolf SR et al. Sniffin Sticks‘: Olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold. Chem Senses 1997; 22(1): 39–52. doi: 10.1093/ chemse/ 22.1.39.

28. Vodička J, Menšíková A, Balatková Z et al. Fyziologické hodnoty čichových testů v české populaci. Otorinolaryngol Foniat 2011; 60(3): 119–124.

29. Katotomichelakis MI, Simopoulos E, Tripsianis G et al. Predictors of quality of life outcomes in chronic rhinosinusitis after sinus surgery. Eur Arch Otorhinolaryngol 2014; 271(4): 733–741. doi: 10.1007/ s00405-013-2626-6.

30. Kim BG, Kang JM, Shin JH et al. Do sinus computed tomography findings predict olfactory dysfunction and its postoperative recovery in chronic rhinosinusitis patients? Am J Rhinol Allergy 2015; 29(1): 69–76. doi: 10.2500/ ajra.2015.29.4120.

31. Kohli P, Naik AN, Harruff EE et al. The prevalence of olfactory dysfunction in chronic rhinosinusitis. Laryngoscope 2017; 127(2): 309–320. doi: 10.1002/ lary.26316.

32. Lind H, Joergensen G, Lange B et al. Efficacy of ESS in chronic rhinosinusitis with and without nasal polyposis: a Danish cohort study. Eur Arch Otorhinolaryngol 2016; 273(4): 911–919. doi: 10.1007/ s00405-015-3667-9.

33. Vandenhende-Szymanski B, Hochet B, Chevalier D
et al. Olfactory cleft opacity and CT score are predictive factors of smell recovery after surgery in nasal polyposis. Rhinology 2015; 53(1): 29–34. doi: 10.4193/ Rhin14.
160.

34. Hummel T, Kobal G, Gudziol H et al. Normative data for the “Sniffin’ Sticks” including tests of odor identification, odor discrimination, and olfactory thresholds:
An upgrade based on a group of more than 3,000 subjects. Eur Arch Otorhinolaryngol 2007; 264(3): 237–243. doi: 10.1007/ s00405-006-0173-0.

35. Rudmik L, Smith TL. Olfactory improvement after endoscopic sinus surgery. Curr Opin Otolaryngol Head Neck Surg 2012; 20(1): 29–32. doi: 10.1097/ MOO. 0b013e32834dfb3d.

36. Schriever N, Gupta N, Pade J et al. Olfactory function following nasal surgery: a 1-year follow-up. Eur Arch Otorhinolaryngol 2013; 270(1): 107–111. doi: 10.1007/ s00405-012-1972-0.

Labels
Paediatric neurology Neurosurgery Neurology

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Czech and Slovak Neurology and Neurosurgery

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