Quality of Life after Deep Brain Stimulation in Patients with Advanced Parkinson’s Disease


Authors: M. Baláž ;  M. Bočková ;  M. Bareš ;  I. Rektorová ;  V. Dírerová ;  I. Rektor
Authors‘ workplace: Centrum pro abnormní pohyby a parkinsonizmus I. neurologická klinika LF MU a FN u sv. Anny v Brně
Published in: Cesk Slov Neurol N 2011; 74/107(5): 564-568
Category: Short Communication

Overview

Goal:
The object of the study was to describe the effect of deep brain stimulation of the subthalamic nucleus on various aspects of quality of life in patients with Parkinson’s disease.

Patients and methods:
Quality of life was assessed by means of the PDQ-39 questionnaire for 26 patients 12 and 36 months after deep brain stimulation to treat advanced Parkinson’s disease.

Results:
Patient quality of life, according to the PDQ-39 summary index, improved by 46% three years after surgery (p <0.001). UPDRS III scores improved by 39% in the first year, and by 31% in the third year after DBS (p <0.001).

Conclusion:
We observed statistically significant improvements in quality of life for all patients both 12 and 36 months after deep brain stimulation. The improvement was most conspicuous in the motor subscales. However, benefit in the social aspects of Parkinson’s disease (stigma, social support, communication) was also evident. Deep brain stimulation appears to have a long-lasting positive effect on the quality of life in patients with Parkinson’s disease.

Key words:
deep brain stimulation – quality of life – Parkinson’s disease


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Labels
Paediatric neurology Neurosurgery Neurology

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