Prevention and treatment of osteoporosis: causal or symptomatic?

Authors: Štěpán Jan
Authors‘ workplace: Revmatologický ústav a 1. LF UK, Praha
Published in: Clinical Osteology 2019; 24(2): 69-73


The severity of the health and socio-economic consequences of osteoporosis in women and in men increases with increasing life expectancy and the ageing of the population. The potential to reduce these risks is with causal measures. Syndrome of osteoporosis represents clinical manifestation of aging (involutional osteoporosis) and chronic diseases (secondary osteoporosis). In subjects with involutional bone loss, the physical activity and low inflammatory index diet appears an effective causal measure in the prevention of osteoporosis and fractures. In secondary osteoporosis, an effective first-line option is treatment of the underlying disease; during early postmenopause hormonal therapy or selective estrogen receptor modulators should be considered. Otherwise, in people with significantly high fracture risk, symptomatic antiresorptive or bone anabolic therapy is available.


fracture risk – involutional osteoporosis – prevention of osteoporosis – secondary osteoporosis – treatment of osteoporosis

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