Drug interactions with a focus on selected drug groups in cardiology

Authors: Juřica J.
Authors‘ workplace: Farmakologický ústav, LF MU, Ústav humánní farmakologie a toxikologie, FarmF MU, Ústavní lékárna, Masarykův onkologický ústav
Published in: Kardiol Rev Int Med 2020, 22(3): 97-102


The risk of drug interactions increases with the number of drugs used. The numbers vary between studies, however, according to one study, the risk of drug interaction with concomitant use of up to five drugs is only 4%, rising to 10% with 5–10 different drugs, over 28% in the group using 11–15 drugs and up to 54% when taking 16–20 different drugs. There are many reasons and possible explanations and each system has its own specifics. The aim of this article is to summarize the basic types of interactions and to give examples of drug interactions in cardiology.


Anticoagulants – proton pump inhibitors – Drug interactions – Diuretics – hypolipidemics – cardiology – antihypertensives – antiarrhythmics – antiagregation


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