Pulmonary hypertension and obstructive sleep apnoea syndrome

Czech version

Authors: Genzor S. ¹; Sova M. ¹; Kolek V. ¹; Hutyra M. ²
Authors‘ workplace: Klinika plicních nemocí a tuberkulózy LF UP a FN Olomouc ¹; I. interní klinika – kardiologická LF UP a FN Olomouc ²
Published in: Kardiol Rev Int Med 2019, 21(3): 121-124

Overview

Obstructive sleep apnoea syndrome (OSAS) is commonly associated with development of pulmonary hypertension (PH). PH is frequently connected with higher cardiovascular morbidity and mortality. In this review, we summarize the main pathophysiological mechanisms leading to higher incidence of PH in OSAS patients, the clinical consequences of the relationship between OSAS and PH, and recommendations for clinical practice. The therapy of OSAS patients has to be complex and it is necessary to include PH diagnostics in diagnostic algorithms for these patients. In cases of clinically significant PH uncontrollable by OSAS therapy, PH-specific therapy is recommended.

Keywords:

sleep apnoea – Pulmonary hypertension – positive airway pressure therapy

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