Specifics of anaesthesia and intensive care in organ transplant patients
Authors:
E. Kieslichová; E. Uchytilová; P. Píza; P. Vychodil
Authors‘ workplace:
Klinika anesteziologie, resuscitace a intenzivní péče, Transplantcentrum, Institut klinické a experimentální medicíny
Published in:
Anest. intenziv. Med., 29, 2018, č. 6, s. 328-337
Category:
Overview
Solid organ transplantation is the only way to treat end-stage organ disease. Survival of the patients with a transplanted organ has improved significantly in the last decades. It has been mainly due to the careful selection of organ transplant candidates from the waiting lists, improved surgical techniques and advances in intensive care and immunosuppressive therapy. This has logically led to an increase in the number of these patients on the follow-up, treated in the emergency departments and admitted to hospitals and intensive care units. The anaesthetic and intensive care management of the transplant recipients is similar to standard practice but there are physiological and pharmacological specific aspects including the adverse effects of immunosuppression, the risk of infection and the risk of rejection which the anaesthetist and the intensivist should consider. One of the most common reasons for hospital admission of the transplanted patients is infection and sepsis, the most common cause of morbidity and mortality in these patients. The cornerstones in the treatment of sepsis are early pathogen identification, infection source control and supportive therapy including temporary withdrawal of the immunosuppressive therapy.
keywords
solid organ transplantation – immunosuppressive therapy – anaesthesia and intensive care, sepsis
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Anaesthesiology, Resuscitation and Inten Intensive Care MedicineArticle was published in
Anaesthesiology and Intensive Care Medicine
2018 Issue 6
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