Authors: J. Mannová 1; Z. Šilhart 2; P. Ševčík 1 Authors‘ workplace: Klinika anesteziologie, resuscitace a intenzivní medicíny MU v Brně a Fakultní nemocnice Brno 1; Chirurgická klinika MU v Brně a Fakultní nemocnice Brno 2 Published in: Anest. intenziv. Med., 18, 2007, č. 3, s. 141-149 Category: Anaesthesiology - Original Paper
Objective:To test the hypothesis that patients with acute normovolaemic haemodilution (ANH) tolerate better aortic clamping and declamping during abdominal aortic aneurysm (AAA) repair. Perioperative haemodynamic changes are mitigated, thus the frequency of ischaemic events and cardiovascular complications are decreased in comparison with the group of patients without ANH.
Design: Prospective randomized study.
Setting: Department of Anesthesiology, Resuscitation and Intensive Medicine, University Hospital.
Materials and methods: 50 patients admitted for elective AAA repair were prospectively randomized into two groups: patients in group A (n = 25) were treated with ANH and patients in group B (n = 25) were not. We monitored the following parameters: BP, MAP, HR, SV, CO, CI, TSVR (HemoSonicTM100, 400 measurements), troponin I level, transfusion requirements and 30-day mortality. Statistical analysis was made using Wilcoxon’s rank sum test, Mann-Whitney test and Fisher test.
Results: After aortic clamping a statistically significant increase in the systolic BP and TSVR, and a decrease in SV, CO and CI occurred in both groups (p
Conclusion: We did not demonstrate a statistically significant difference in haemodynamic changes, the frequency of perioperative or postoperative complications, and ischaemic events between two groups of patients treated with and without ANH.
Key words: abdominal aortic aneurysm – acute normovolaemic haemodilution – haemodynamic parameters – transesophageal doppler – troponin I
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