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Medical News

krev

Untreated Bleeding in Hemophilia A –⁠ An Underestimated Problem? To What Extent?

27. 11. 2023 Source: Hemophilia

How common is bleeding in hemophilia A that ultimately goes untreated? This was the focus of a recent study, the results of which were published in the journal Research and Practice in Thrombosis and Hemostasis.

krev

Economic Costs and Concomitant FVIII Consumption in Hemophilia Patients Treated with Emicizumab in the 1st Year −⁠ A US Experience

The authors of a recent study, summarizing real-world experience from the US, focused on the concomitant consumption of FVIII (Factor VIII) concentrates during emicizumab prophylaxis and the…
27. 11. 2023 Source: Hemophilia
doktorka žena

Minimally Invasive Treatment of Pilonidal Sinus: Laser and Negative Pressure Therapy as a Gentle and Effective Modality

The increasing incidence of pilonidal sinus contributes to the development of new treatment methods. Experiences from AGEL Hospital Přerov show that the methods SiLaC (sinus laser ablation of the…
24. 11. 2023 Source: Wound Healing
artritidakkk

Reduction of Enthesitis in Patients with Psoriatic Arthritis Taking Tofacitinib

Inflammation in the area where a tendon, ligament, or joint capsule attaches to the bone occurs in 35–50% of patients with psoriatic arthritis (PsA). Its presence is associated with higher activity…
24. 11. 2023 Source: Arthritis
psychika a obezita

How do body weight and metabolic parameters change in patients first hospitalized for psychosis?

The most common cause of death in patients with schizophrenia is cardiovascular disease, which is closely related to obesity or metabolic syndrome. The study presented below examined changes in body…
24. 11. 2023 Source: Modern Treatment of Schizophrenia

Prof. Hana Rosolová: According to recent studies, caution is needed with beta-blockers only in severe cases of asthma and COPD

Beta-blockers (BB) are among the most widely used drug groups in cardiology. While their position is clear in some indications, it is debated in others. Additionally, individual BBs differ in various…
23. 11. 2023 Source: Cardiovascular Continuum
artritidaTT

Reduction of Inflammation in Vertebral Bodies and Posterolateral Structures of the Spine in Patients with Ankylosing Spondylitis Treated with Tofacitinib

A post hoc analysis of a phase II study with tofacitinib in patients with active ankylosing spondylitis (AS) evaluated the suppression of spinal inflammation using magnetic resonance imaging (MRI)…
23. 11. 2023 Source: Arthritis
nemocnicniprostredi

How Do Patients Themselves Perceive Today's Treatment Options for ITP and What Are Their Biggest Fears?

What is the perception and view of the treatment options for immune thrombocytopenia (ITP) from the patients' perspective, what do they fear, what approaches do they prefer, and why? Lozano et al.…
21. 11. 2023 Source: Immune Thrombocytopenia
krev

Romiplostim brings benefit also to patients with ITP lasting less than 1 year

What is the role of second-line therapy, in this case romiplostim, in the management of adult ITP patients who have not yet reached the chronic phase of the disease?
21. 11. 2023 Source: Immune Thrombocytopenia
amyloid

Stabilization of Transthyretin and Long-term Survival of Patients with Cardiac Amyloidosis

Tafamidis is used in the therapy of transthyretin amyloid cardiomyopathy (ATTR-CM), which has proven its benefit in the ATTR-ACT clinical study. The results of its open-label extension study show…
20. 11. 2023 Source: Amyloidosis
karcinom

HVD 2023: Cervical Cancer May Be the First Eliminated Malignancy. What Paths Will Lead to This Goal in the Czech Republic?

Cervical cancer is the 3rd most common cancer among women aged 15–44. Annually, it is diagnosed in 750–800 women in our country, and every 29 hours, one woman dies from it in the Czech Republic.…
15. 11. 2023 Source: Regular Vaccination
oko

Drops with Liposomal Ozonized Oil Reduce Ocular Microbial Burden Before Cataract Surgery

The periocular zone and conjunctiva are characterized by high microbial activity. Therefore, it is important to reduce this bacterial burden as part of preoperative prophylaxis before surgery to…
14. 11. 2023 Source: Treatment of Glaucoma
studie_osteoporoza

Post hoc Analysis of the FRAME Study –⁠ Romosozumab in the Treatment of Osteoporosis in the European Population

An interesting finding from the FRAME study, which evaluated the treatment of postmenopausal women with osteoporosis using romosozumab, was the significant differences in fracture incidence among…
14. 11. 2023 Source: Osteoporosis – Trends in Sequential Therapy
kost

Romosozumab vs. Teriparatide in Sequential Treatment of Osteoporosis in Women with a History of Fracture

The STRUCTURE study observed the effect of romosozumab and teriparatide on bone density in postmenopausal women with osteoporosis transitioning from bisphosphonate treatment over a 12-month period.
14. 11. 2023 Source: Osteoporosis – Trends in Sequential Therapy
srdce

How Important is the Time Factor in the Treatment of Heart Failure?

Current guidelines emphasize the importance of early diagnosis and immediate treatment for patients with heart failure (HF). These patients are most vulnerable immediately after the decompensation of…
13. 11. 2023 Source: Heart Failure
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