Medical News
Use of Testosterone Level as a Biomarker for Quality of Life in Patients with Prostate Cancer
In the treatment of prostate cancer, in addition to surgical treatment, stereotactic body radiotherapy (SBRT) and hormone therapy are also used. Androgen deprivation therapy (ADT) blocks the action or production of male sex hormones and is indicated for the treatment of intermediate and high-risk prostate cancers, where it reduces the risk of metastasis and prolongs survival. The work of experts from several American institutions monitored testosterone levels during therapy and their connection to the development of quality of life scores.
How Does Empagliflozin Stand in Terms of Diabetic Retinopathy Risk? We Have Answers Not Only from Controlled Studies but Also from Real Practice
Modern antidiabetics – gliflozins and glucagon-like peptide-1 receptor agonists (GLP-1RA) – significantly help improve the management of type 2 diabetes (DM2). In addition to reliable glycemic…
The Significance of Administering Gliflozins in Real Practice in Diabetics Without CV and Renal Disease
Current care standards recommend the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i, i.e., gliflozins) regardless of glycemic compensation in patients with type 2 diabetes (T2DM) and kidney…
Doc. Miloslav Salavec: We Still Encounter Delayed Initiation of Biological Treatment in AD and Many Other Diagnoses
Not all patients with atopic dermatitis (AD) who are indicated for biological treatment with dupilumab manage to reach centers where the treatment is provided. It's even more unfortunate when there's…
Dual Inhibition of IL-17A/IL-17F Across the Spectrum of Axial Spondyloarthritis
Many patients with axial spondyloarthritis (axSpA) still have a need to seek additional therapeutic options and new mechanisms of action for medicinal substances. Phase III studies BE MOBILE 1 and 2…
Effectiveness and Safety of Initiating Treatment for Primary Immunodeficiency with Subcutaneously Administered Immunoglobulins – A Systematic Review of the Literature
The aim of the systematic review of the literature published last year was to evaluate the effectiveness and safety of initiating treatment with subcutaneously administered immunoglobulins (SCIG) in…
10 Warning Signs of Primary and Secondary Immunodeficiencies
The Jeffrey Modell Foundation (JMF) proposed 10 warning signs of primary immunodeficiencies (PID). The study presented below examined whether they are applicable to secondary immunodeficiencies (SID)…
Picking from the Red Book of the CHS: What's New in This Year's Recommendations for Diagnosis and Treatment of AML?
In recent years, there have been significant advances in the diagnosis and therapy of acute myeloid leukemia (AML). High-quality laboratory diagnostics (molecular genetics, cytogenetics, and flow…
Educational Brochure for Patients with CLL
Thanks to the expansion of modern therapies for chronic lymphocytic leukemia, many patients now have regimens based on venetoclax. Do you want to help them better understand the practical aspects and...
Bacterial Biofilm as a Complication of Respiratory Disease Treatment
One of the unique characteristics of certain microorganisms is their ability to form organized communities enveloped in extracellular polymeric matrix and firmly attached to a solid surface or…
Impact of erdostein on bacterial biofilm − and what it means for clinical practice?
One of the substances that could potentially influence the success of treatments for infections associated with biofilm formation in the future is erdostein. This medication is used in the treatment…
Low Molecular Weight Heparin in an ECMO Patient − Case Study
Extracorporeal membrane oxygenation (ECMO) has an irreplaceable role in intensive care medicine. In the context of preventing complications caused by blood clot formation, unfractionated heparin is…
Use of Enoxaparin in Patients After Implantation of Left Ventricular Assist Device
Left ventricular assist devices (LVAD) are utilized in patients with end-stage heart failure (HF). Warfarin is typically employed for long-term anticoagulation, but there are no standardized…
Prophylaxis with Enoxaparin After Total Knee or Hip Replacement
Venous thromboembolic disease is a significant cause of complications in surgical patients during and after hospitalization. The authors of a recently published Portuguese observational study…
What Are the Impacts of Not Administering Extended VTE Prophylaxis in Oncology Patients After GIT Surgeries?
In a freshly published retrospective study, experts from the University of Arkansas investigated how well the professional recommendation that cancer patients undergo extended venous thromboembolism…