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RADIOFREQUENCY ABLATION OF RENAL TUMOURS


Authors: A. Čermák *;  D. Pacík
Authors‘ workplace: Urologická klinika FN Brno *
Published in: Urol List 2012; 10(1): 31-35

Overview

An increasing incidence of localized renal cancer during the last three decades and the mortality of this disease has triggered the evaluation of current treatment modalities. The standard therapy for small focal lesions is surgical excision with the aim of sparing the renal parenchyma. Urologists are continuously searching for new alternative methods to substitute classical surgical treatment. They are searching for less aggressive approaches, posing less of a burden to the patient and methods, which can be used in conditions in which the classical or laparoscopic approach is associated with undesirable burden. Alternatives to the surgical treatment of small renal masses include methods, which are based on different physical principles of tissue destruction. These methods can be applied either laparoscopically or percutaneously. The most frequently used methods in clinical practice include radiofrequency ablation and cryoablation. Also other methods are being tested, such as high intensity focused ultrasound, microwave thermotherapy, interstitial photon radiation and laser interstitial ablation. Efficacy of these novel approaches should be comparable to classical surgery. With further improvement of these techniques the long-term results, their benefit and disadvantages are evaluated and new evidence is being collected regarding the efficacy of individual techniques under individual conditions. The alternative, less invasive methods seem to be solution in selected cohorts of high-risk patients, allowing to reduce their morbidity.

Key words:
renal cell carcinoma, small renal mass, radiofrequency ablation, miniinvasive therapy, nephron-sparing surgery, cryotherapy, biopsy


Sources

1. Sobotka R. Hanuš T. Nádory ledvin in Postgraduální medicína 2001; 1: 48.

2. Morávek P, Morávek P Jr, Dvořák P et al. Perkutánní radiofrekvenční ablace (RFA) v léčbě nádorů ledvin – vlastní zkušenosti. Ces Urol 2010; 14(2): 104–109.

3. Ljungberg B, Cowan NC, Hanbury DC et al. EAU guidelines on renal cell carcinoma: the 2010 update. Eur Urol 2010; 58(3): 398–406.

4. Campbell SC, Novick AC, Belldegrun A et al. Guid­e­line for management of the clinical T1 renal mass. J Urol 2009; 182(4): 1271–1279.

5. Volpe A, Cadeddu JA, Cestari A et al. Contemporary Management of Small Renal Masses European Urology 2011; 60(3): 501–515.

6. Aron M, Gill IS. Minimally invasive nephron-sparing surgery (MINSS) for renal tumours. Part II: probe ablative therapy. Eur Urol 2007; 51(2): 348–357.

7. Zlotta AR, Wildschutz T, Raviv G et al. Radio­fre­quency interstitial tumor ablation (RITA) is a possible new modality for treatment of renal cancer: ex vivo and in vivo experience. J Endourol 1997; 11(4): 251.

8. deBaere T, Kuoch V, Smayra T et al. Radio frequency of renal cell carcinoma: preliminary clinical expe­rience. J Urol 2002; 167(5): 1961–1964.

9. Gill IS, Novick AS, Soble JJ et al. Laparoscopic renal cryoablation: initial clinical series. Urology 1998; 52(4): 543–551.

10. Goldberg SN, Gazelle GS, Mueller PR. Thermal abla­tion therapy for focal malignancy: a unified approach to underlying principles, techniques, and diagnostic imaging guidance. AJRAmJ Roentgenol 2000; 174(2): 323–331.

11. Rendon RA, Gertner MR, Sherak MD et al. Deve­lop­ment of a radiofrequency based thermal therapy technique in an in vivo porcine model the treatment of small renal masses. J Urol 2001; 166(1): 292–298.

12. Jacomides L, Ogan K, Watumull L et al. Laparo­scopic application of radio frequency energy enables in situ renal tumor ablation and partial nephrectomy. J Urol 2003; 169(1): 49–53.

13. Hora M, Hes O, Klečka J. Miniinvazivní ledvinu šetřící ablační metodiky v léčbě nádorů ledvin. Urol list 2003; 2(1): 26–29.

14. Kunkle DA, Uzzo RG. Cryoablation or radiofrequency ablation of the small renal mass: a meta-analysis. Cancer 2008; 113(10): 2671–2680.

15. Long L, Park S. Differences in patterns of care: reablation and nephrectomy rates after needle ablative therapy for renal masses stratified by medical specialty. J Endourol 2009; 23(3): 421–426.

16. Tracy CR, Raman JD, Donnally C et al. Durable oncologic outcomes after radiofrequency ablation: experience from treating 243 small renal masses over 7.5 years. Cancer 2010; 116(13): 3135–3142.

17. Zagoria RJ, Traver MA, Werle DM et al. Oncologic efficacy of CT-guided percutaneous radiofrequency ablation of renal cell carcinomas. AJR Am J Roentge­nol 2007; 189(2): 429–436.

18. Rendon RA, Kachura JR, Sweet JM et al. The uncertainty of radiofrequency treatment of renal cell carcinoma: findings at immediate and delayed nephrectomy. J Urol 2002; 167(4): 1587–1592.

19. Matlaga BR, Zagoria RJ, Woodruff RD et al. Phase II trial of radio frequency ablation of renal cancer: eva­lua­tion of the kill zone. J Urol 2002; 168(6): 2401–2405.

20. Klingler HC, Marberger M, Mauermann J et al.‘Skipping’ is still a problem with radiofrequency ablation of small renal tumours. BJU Int 2007; 99(5): 998–1001.

21. Weight CJ, Kaouk JH, Hegarty NJ et al. Correlation of radiographic imaging and histopathology following cryoablation and radio frequency ablation for renal tumors. J Urol 2008; 179(4): 1277–1281.

22. Stern JM, Gupta A, Raman JD et al. Radio­fre­quency ablation of small renal cortical tumours in healthy adults: renal function preservativ and intermediate oncological outcome. BJU Int 2009; 104(6): 786–789.

23. Johnson DB, Solomon SB, Su LM et al. Defining the complications of cryoablation and radiofrequency ablation of small renal tumors: a multi-institutional review. J Urol 2004; 172(3): 874–877.

24. Gill IS, Remer EM, Hasan WA et al. Renal cryoablation: outcome at 3 years. J Urol 2005; 173(6): 1903–1907.

25. Hora M, Hes O, Ürge T et al. A distinctive translocation carcinoma of the kidney (‘rosette-like forming’, t(6;11), HMB45 positive renal tumor). Int Urol Nephrol 2009; 41(3): 553–557.

26. Kawaciuk I. Prognóza karcinomu ledviny. Praha: Galén 2005.

27. Kolombo I, Kříž R, Janoušková L et al. Selective embolization and radiofrequency ablation of renal mass in polymorbid and elderly patients – our experience. Eur Urol Meetings 2007; Abstracts of the EAU 7th Central European Meeting 26–27 October 2007, Zagreb, Croatia; 2(7): abstract 26.

28. Kolombo I, Hanuš T, Odrážka K. Karcinom ledviny. Praha: Mladá fronta 2010.

29. Dvořáček J, Babjuk M. Onkourologie. Praha: Galén 2005.

30. Gronka L, Poršová M, Kolombo I et al. Karcinom ledviny – současné trendy: Urologie pro praxi; 9(3): 120–127.

31. Poppel H, Becker F,Cadeddu JA et al. Treatment of Localised Renal Cell Carcinoma. Eur Urol 2011; 60(4): 662–672.

32. Epidemiologie zhoubných nádoru v České Re­pu­-b­lice. Report diagnózy: C64 – ZN ledviny mimo pánvičku.

33. International Agency for Research on Cancer, GLOBOCAN 2008. http://www.iarc.fr.

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