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Therapeutic Options for Advanced Prostate Cancer. Management of locally advanced and androgen dependent prostate cancer


Authors: L. Klotz;  K. Pienta
Authors‘ workplace: Division of Urology Sunnybrook Health Sciences Centre, Toronto
Published in: Urol List 2009; 7(3): 15-23

Overview

The author in his article presents an overview of therapeutic options for the treatment of locally advanced prostate cancer, which represents a heterogeneous group of tumors. In most patients is usually indicated combination treatment with androgen deprivation playing an important role. It is important and not easy to estimate what form will be the most suitable for particular patient, concerning alternative of combination treatment and its timing. Very important role in decision can be contributed to PSA kinetics. Based on previous and current clinical studies, the author tries to answer question which form of hormonal deprivation is appropriate in which patient. Last but not least he deals with the issue how to identify, treat and follow up androgen independent tumors.

Key words:
locally advanced prostate cancer, androgen dependency, timing of hormonal treatment, alternatives of androgen deprivation


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