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Quantitative analysis of chimerism after allogenichematopoietic cells transplantation
Authors: O. Horký; D. Dvořáková; J. Mayer
Authors‘ workplace: Centrum molekulární biologie a genové terapie, Interní hematoonkologická klinika, FN Brno
Published in: Transfuze Hematol. dnes,, 2004, No. 2, p. 70-75.
Category:
Overview
Examination of chimerism has become an integral element of the monitoring of patients after allogenichematopoietic cell transplantation. Presented publication initially describes different methods ofchimerism evaluation. In the second part, there is detailed characterization of the capillary electrophoresiswith fluorescence detection (fragment analysis) of amplification products of high polymorficmicro - and mini - satellite DNA regions, technique, which become the gold standard for quantitativeevaluation.
Key words:
chimerism, STR and VNTR polymorphism, fragment analysis
Labels
Haematology Internal medicine Clinical oncology
Article was published inTransfusion and Haematology Today
2004 Issue 2-
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Most read in this issue- Translocation of t(14;18) and its importance infollow up of minimal residual disease in follicular lymphoma
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- Quantitative analysis of chimerism after allogenichematopoietic cells transplantation
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