How women respond to combined NuvaRing^® contraception

Czech version

Authors: MUDr. Tomáš Fait
Authors‘ workplace: Gynekologicko-porodnická klinika 1. LF UK a VFN v Praze
Published in: Prakt Gyn 2008; 12(1): 33-35

Overview

Review of data from relevant literature in the Medline scientific database contains results of studies confirming high contraceptive efficacy of NuvaRing comparable with oral combined contraception, as well as better control of the cycle and minimal changes in the vaginal environment.

Key words:
combined contraceptive – vaginal ring – effi cacy – tolerability

Sources

1. Timmer CJ, Mulders TM. Pharmacokinetics of etonogestrel and ethinylestradiol released from a combined contraceptive vaginal ring. Clin Pharmacokinet 2000; 39: 233-242.

2. Miller L, Verhoeven CH, Hout J. Extended regimens of the contraceptive vaginal ring. Obstet Gynecol 2005; 106(3): 473-482.

3. Roumen FJ, Apter D, Mulders TM et al. Efficacy, tolerability and acceptability of a novel contraceptive vaginal ring releasing etonogestrel and ethinylestradiol. Hum Reprod 2001; 16: 469-475.

4. Ahrendt HJ, Nisand I, Bastianelli C et al. Efficacy, acceptability and tolerability o the combined contraceptive ring, NuvaRing, compared with an oral contraceptive containing 30 µg of ethinylestradiol and 3 mg of drospirenone. Contraception 2006; 74: 451-457.

5. Milson I, Lete I, Bjertnaes A et al. Effects on cycle control and bodyweight o the contraceptive ring, NuvaRing, versus an oral contraceptive containing 30 µg ethinylestradiol and 3 mg drospirenon. Hum Reprod 2006; 21(9): 2304-2311.

6. Oddson K, Leifels-Fischer B, Wiel-Masson D et al. Superior cycle kontrol with a contraceptive vaginal ring compared with an oral contraceptive containing 30µg ethinylestradiol and 150µg levonorgestrel:a randomized trial. Hum Reprod 2005; 20(2): 557-562.

7. Bjarnadottir RI, Tuppurainen M, Killick SR. Comparison of cycle control with combined contraceptive vaginal ring and oral levonorgestrel/ethinylestradiol. Am J Obstet Gynecol 2002; 186: 389-395.

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9. Archer DF, Raine T, Darney PJ et al. An open- labeled noncomparative study to evaluate the vagina and cervix of NuvaRing users. Fertil Steril 2002; 78(Suppl 1): S25.