Is obesity an adverse prognostic factor for pulmonary manifestations of influenza?
Lesson from complicated disease course H1N1
Authors:
Renata Zoubková 1,2; Jan Máca 1,2; Petr Handlos 3; Lenka Rudinská 3; Ivana Nytra 1,2; Václav Chýlek 1,2; Jana Vavrošová 2
Authors‘ workplace:
Katedra intenzivní medicíny a forenzních oborů Lékařská fakulta Ostravské univerzity v Ostravě
1; Klinika anesteziologie, resuscitace a intenzivní medicíny FN Ostrava
2; Ústav soudního lékařství FN Ostrava a Lékařská fakulta Ostravské univerzity v Ostravě
3
Published in:
Čas. Lék. čes. 2014; 153: 277-283
Category:
Case Report
Overview
Influenza viruses cause annual epidemics that occur at different times in both the northern and southern hemisphere. In cases of seasonal influenza these are usually mild forms of the disease, which rarely lead to death of the patient. Vulnerable groups include the elderly, the young or those with comorbidities, where the virus affects tens of thousands of victims around the world. Occasionally, however, large epidemics appear caused by a dangerous variant of a new virus, which is usually characterized by high contagiousness and pathogenicity (virulence). Consequently, it is often accompanied by a complicated disease course and associated with high mortality. In 2009, a viral pandemic disease marked pH1N1 2009 Influenza A appeared. Even though the initial predictions were far worse, the course of influenza caused by this virus was often complicated by acute respiratory failure in the form of acute respiratory distress syndrome (ARDS). This formed part of the wider multiple organ failure syndrome (MODS). This type of virus often infects younger age groups and is more contagious compared to the seasonal flu. In order to illustrate the complicated forms of viral infections pH1N1 2009 Influenza A we present three case studies which demonstrate complicated pulmonary manifestation, which take the primary form of ARDS.
Keywords:
influenza A pH1N1 2009 – pandemic pH1N1 2009 – obesity – lung histology
Sources
1. WHO: Pandemic (H1N1) 2009 – update 101 (http://www.who.int/csr/don/2010_05_21/en/index.html)
2. Beran J. Chřipka, 2. rozš. vyd. Praha: Maxdorf 2002.
3. Kathy Hancock, Vic Veguilla, Xiuhua Lu, Weimin Zhong, et al. Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus. N Engl J Med 2009; 361: 1945–1952.
4. Chowell G, Bertozzi SM, Colchero M, et al. Severe respirátory dinase concurrent with circulation of H1N1 influenza. N Engl J Med 2009; 361: 674–679.
5. Perez-Padilla R, Rosa-Zamboni D, Ponce de Leon S, et al. Pneumonia and respiratory silure from swine-origin influenza A (H1N1) in Mexiko.N Engl J Med 2009; 361: 680–689.
6. Dominguez-Cherit G, Lapinsky SE, Macias AE, Pinto R, Espinosa-Perez L, de la Torre A, et al. Critically Ill Patients With 2009 Influenza A(H1N1) in Mexico. JAMA 2009; 302: 1880–1887.
7. Gomez-Gomez A, Magana-Aquino M, Garcia-Sepulveda CA, Ochoa-Perez UR, Falcon-Escobedo R, Comas-Garcia A, et al. Severe pneumonia associated with pandemic (H1N1) 2009 outbreak, San LuisPotosí, Mexico. Emerg Infect Dis 2010; 16: 27–34.
8. Jain S, Kamimoto L, Bramley AM, Schmitz AM, Benoit SR, Louie J, et al. Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009. N Engl J Med 2009; 361: 1935–1944.
9. Kopel E, Amitai Z, Grotto I, Kaliner E, Volovik I. Patients with Pandemic (H1N1) 2009 in intensive care units, Israel. Emerg Infect Dis 2010; 16: 720–721.
10. Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J, Stelfox T, et al. Critically ill patients with 2009 infl uenza A (H1N1) infection in Canada. JAMA 2009; 302: 1872–1879.
11. Louie JK, Acosta M, Winter K, Jean C, Gavali S, Schechter R, et al. Factors associated with death or hospitalization due to pandemic 2009 influenza A (H1N1) infection in California. JAMA 2009; 302: 1896–1902.
12. Rello J, Rodriguez A, Ibanez P, Socias L, Cebrian J, Marques A,et al. Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain. Crit Care 2009; 13: R148.
13. Yeung JHY, Bailey M, Perkins GD, Smith FG. Presentation and management of critically ill patients with influenza A (H1N1): a UK perspective. Crit Care 2009; 13: 426.
14. Zarychanski R, Stuart TL, Kumar A, Doucette S, Elliott L, Kettner J, et al. Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infection. Canad Med Assoc J 2010; 182: 257–264.
15. Webb SA, Pettila V, Seppelt I, Bellomo R, Bailey M, Cooper DJ,et al. Critical care services and 2009 H1N1 infl uenza in Australia and New Zealand. N Engl J Med 2009; 361: 1925–1934.
16. SZÚ: Aktualizované informace – potvrzené případy onemocnění virem „Pandemic (H1N1) 2009“ ke dni 3. 3. 2010 (http://www.szu.cz/tema/prevence/aktualizovane-informace-o-potvrzenych-pripadech-onemocneni-2)
17. CDC. Intensive-care patients with severe novel influenza A (H1N1) virus infection – Michigan, June 2009. MMWR Morb Mortal Wkly Rep 2009; 58: 749–752.
18. Mauad T, Hajjar LA, Callegari GD, da Silva LF, Schout D, Galas FR,et al. Lung pathology in fatal novel human influenza A (H1N1) infection. Am J Respir Crit Care Med 2010; 181: 72–79.
19. CDC. Prevention and control of influenza: recommendations of the advisory committee on immunization practices (ACIP), 2008. MMWR Morb Mortal Wkly Rep 2008; 57(No. RR-7).
20. Petersen E. Optimal management of severe H1N1. European Congress on Clinical Microbiology and Infectious Diseases, Vienna, 10.–13. 4. 2010.
21. WHO Guidelines for pharmacological management of pandemic influenza A (H1N1) 2009 and other influenza viruses. (http://www.who.int/csr/resources/publications/swineflu/h1n1_guidelines_pharmaceutical_mngt.pdf)
22. Rello J, Pop-Vicas A. Clinical review: Primary influenza viral pneumonia. Critical Care 2009; 13: 235.
23. Fabiánová K. Prasečí chřipka (online). Státní zdravotní ústav, 25. 4. 2009, rev. 27. 4. 2009 (cit. 2009-04-28).
24. Situation updates – Influenza A (H1N1). WHO (online)/cit. 6. září 2006, http://www.who.int/csr/disease/swineflu/updates/en/index.html
25. Kula R, Maca J, Sklienka P, Tichy J, Szturz P, Jahoda J, Czerný D, Chýlek V, Sukenik P. Exogenous surfactant as a component of complex non-ECMO therapy of ARDS caused by influenza A virus (2009 H1N1). Bratisl. Lek. Listy. 2011; 112(4): 218–222.
26. Blechová Z. Chřipka pandemic H1N1 2009. Lékařské listy 2010; 13.
27. Marcelli D, Marelli C, Richards N. Influenza A (H1N1)v pandemic in the dialysis population: first wave results from an international survey. Nephrol Dial Transplant 2009; 12: 3566–3572.
28. Jaber S, Conseil M, Coisel Y, Jung B, Chanques G. ARDS and influenza A (H1N1): patients‘ characteristics and management in intensive care unit. (A literature review). Ann Fr Anesth Reanim 2010; 29(2): 117–125. doi:10.1016/j.annfar.2009.12.026. Epub 2010 Feb 8. Review. French.
29. Morgan OW, Bramley A, Fowlkes A, Freedman DS, Tailor TH, et al. Morbid Obesity as a Risk Factor for Hospitalization and Death Due to 2009 Pandemic Influenza A (H1N1). Disease Plos ONE 5 (3): e9694, doi:10.1371/journal.pone.0009694
30. Fezeu L, et al. Obesity is associated with higher risk of intensive care unit admission and dech in influenza A (H1N1) patients: a systemic review and meta-analysis. Obes Rev 2011; 12(8): 653–659.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain managementArticle was published in
Journal of Czech Physicians
Most read in this issue
- Pancreatic adenocarcinoma – early symptoms and screening
- Overweight, obesity and underweight prevalence in 7-year-old children in the Czech Republic since 1951
-
Is obesity an adverse prognostic factor for pulmonary manifestations of influenza?
Lesson from complicated disease course H1N1