#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Impact of mechanical circulatory support on renal function in a patient with end stage heart failure


Authors: Marián Urban 1;  Ivan Netuka 1,3;  Alena Paříková 2;  Jiří Malý 1,3;  Ondrej Szárszoi 1,3;  Jan Pirk 1,3
Authors‘ workplace: Klinika kardiovaskulární chirurgie IKEM, Praha 1;  Klinika nefrologie IKEM, Praha 2;  Centrum výzkumu srdce a cév 3
Published in: Čas. Lék. čes. 2010; 149: 129-132
Category: Case Report

Overview

Renal insufficiency is common in patients with chronic heart failure. There are two pathologic processes involved in etiology of this type of renal insufficiency: first is the decrease in end organ perfusion as a result of reduction in cardiac output of the failing heart, second is the vascular nephrosclerosis resulting from atherosclerosis as part of the underlying disease process. This paper outlines the benefit of mechanical assist device implantation in improving renal function. After a rapid improvement of renal functions after biventricular assist device implantation in our patient with dilated cardiomyopathy we were able to avoid combined heart and kidney transplant and proceed with an isolated heart transplant.

Key words:
chronic heart failure, chronic renal failure, mechanical assist device, cardiorenal syndrome, combined heart kidney transplant, heart transplant.


Sources

1. Málek F. Má nová definice kardiorenálního syndromu význam pro klinickou praxi? Cor et Vasa 2009; 9: 590–592.

2. Abassi Z, Gurbanov K, Rubinstein I, et al. Regulation of intrarenal blood flow in experimental heart failure: Role of Endothelin and Nitric Oxide. Am J Physiol 1998; 274: F766–F774.

3. Hillege HL, Nitsch D, Pheffer MA, et al. Renal function as a predictor of outcome in a broad spectrum of patiets with heart failure. Circulation 2006; 113: 671–678.

4. Taylor DO, Edwards LB, Boucek MM, et al. International Society for Heart and Lung Transplantation. Registry of the International Society for Heart and Lung Transplantation: Twenty third official adult heart transplantation report – 2006. J Heart Lung Transplant 2006; 25: 869–879.

5. Gill J, Shah T, Hristea I, et al. Outcomes of simultaneous heart-kidney transplant in the US: A Retrospective analysis using UPTN/UNOS data. Am J Transplant 2009; 9: 844–852.

6. Narula J, Bennett LE, DiSalvo T, et al. Outcomes in recipients of combined heart-kidney transplantation: Multiorgan, same donor transplant study of International Society of Heart and Lung Transplantation. Transplantation 1997; 63: 861–867.

7. Leeser DB, Valluvan J, Furukawa S, et al. Simultaneous heart and kidney transplantation in patients with end stage heart and renal failure. Am J Transplant 2001; 1: 89–92.

8. Hsu RB, Tsai MK, Lee PH, et al. Simultaneous heart and kidney transplantation from a single donor. Eur J Cardio Thorac Surgery 2008; 34: 1179–1184.

9. Netuka I, Szárszoi O, Malý J. Mechanické srdeční podpory v terapii terminálního srdečního selhání. Cor Vasa 2008; 50: 207–214.

10. Bergler-Klein J, Pirich C, Laufer G, et al. The long-term effect of simultaneous heart and kidney transplantation on native renal function. Transplantation 2001; 71: 1597–1600.

11. Sandner SE, Zimpfer D, Zrunek P, et al. Renal Function After Implantation of Continuous Versus Pulsatile Flow Left Ventricular Assist Devices. Ann Thorac Surg 2009; 87: 1072–1078.

12. Butler J, Geisberg C, Houwser R, et al. Relationship between Renal Function and LVAD Use. Ann Thorac Surg 2006; 81: 1745–1751.

13. Kettner J, Pirk J, Netuka I, et al. Mechanical cardiac support – the first use in Czech Republic. Čas Lék čes 2005; 144: 38–42.

Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#