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Analytical Methods at the Boundary between Biochemistry and Immunology


Authors: P. Štern 1;  V. Král 2
Authors‘ workplace: Ústav klinické biochemie a laboratorní diagnostiky 1. LF UK a VFN, Praha 1;  Centrum imunologie a mikrobiologie, Zdravotní ústav se sídlem v Ústí nad Labem 2
Published in: Čas. Lék. čes. 2008; 147: 415-420
Category: Topic

Overview

The article presents assays shared by both disciplines; i.e the specialization 801 (Clinical Biochemistry) and 813 (Laboratory of Allergology and Immunology), and it covers over 60 tests. It is intended as reference information for general practitioners, as well as for laboratory workers at the beginning of their studies. Emphasis is laid on some facts which GPs ordering laboratory determinations should be familiar with; the pre-analytical stage (specimen collection, their transport and storage), the analytical reliability of particular methods, their accessibility, frequency and total costs. Analytical techniques are only mentioned marginally as their understanding is not essential for GPs. Assuming the readers’ fundamental experience of diagnostic applications of the methods discussed; we only comment some obsolete or rare tests. The shared assays cover selected analyses of proteins (incl. some enzymes and tumormarkers), ions, osmolality and quantitative microscopic urinalysis.

Key words:
shared laboratory outputs, preanalytical phase, tolerance interval.


Sources

1. Zima, T.: Laboratorní diagnostika. Druhé, doplněné a přepracované vydání, Praha, Galén, s r.o., Univerzita Karlova, nakladatelství Karolinum, 2007, 728 s.

2. Doporučení č. 6 České společnosti klinické biochemie ČLS JEP (ČSKB), Referenční laboratoře MZ pro klinickou biochemii (RL), Sekce pro neuroimunologii a likvorologii České neurologické společnosti ČLS JEP a Sekce laboratorní imunologie České společnosti pro alergologii a klinickou imunologii ČLS JEP (ČSAKI) k vyšetřování mozkomíšního moku.

3. Adam, P., Andrýs, C., Friedecký, B. et al.: Doporučení k vyšetřování mozkomíšního moku. Klin. Biochem. Metab., 2006, 14, s. 125–127.

4. Bartůňková, J., Paulík, M. et al.: Vyšetřovací metody v imunologii. Praha, Grada Publishing, a.s., 2005, 184 s.

Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management
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