Allogeneic Bone Marrow Transplantation
Authors:
A. Vítek
Authors‘ workplace:
Ústav hematologie a krevní transfuze, Praha
Published in:
Čas. Lék. čes. 2003; : 736-740
Category:
Overview
Allogeneic bone marrow transplantation (alloBMT) represents an important part of the therapeutic approaches inmany malignant as well as non-malignant hematological diseases. For some of them it represents the only curativestrategy available, in others it may improve the outcome of treatment in high-risk stages. Curative potential ofalloBMT consists of the curative potential of cytostatic activity of the pre-transplantation treatment and of so-calledgraft versus leukaemia effect (GVL), which is mediated by transplanted lymphocytes. GVL seems to be one of themost effective mechanisms in the treatment of many hematological malignancies and it is therefore studied in thecontext of the nonmyeloablative transplantations (minitransplantations).
Key words:
allogeneic bone marrow transplantation, cytostatic activity, pre-transplantation treatment,leukaemia. Ví.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain managementArticle was published in
Journal of Czech Physicians
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