Dynamic Testing of Liver Function Using Lidocaine Test
; R. Průša
Ústav klinické biochemie a patobiochemie, Praha
Čas. Lék. čes. 2000; : 603-604
Lidocaine clearance test may reflect the integrity of various oxidative pathways of hepatocytes. Lidocaine isa highly sensitive indicator of hepatic dysfunction. This test is applicable to assessment of stage and prognosis ofthe liver disease, to timing of the liver transplantation, and to assessment of the pretransplant prognosis in the end-stageof chronic liver disease. Formation of the major lidocain metabolite monoethylglycinexylidide (MRGX) depends onthe hepatic cytochrome P-450 activity and on the liver blood flow.
lidocaine, monoethylglycinexylidide, liver function, liver transplantation.
Full text is not available online.
If interested in a scan of this journal, contact NTO ČLS JEP
Allergology and clinical immunology
Dermatology & STDs