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Osteoporosis in premenopausal women


Authors: Juraj Payer;  Juraj Smaha;  Martin Kužma;  Zdenko Killinger;  Peter Jackuliak
Authors‘ workplace: V. interná klinika Lekárskej fakulty UK a Univerzitnej nemocnice Bratislava
Published in: Vnitř Lék 2021; 67(5): 284-290
Category: Main Topic

Overview

In contrast to postmenopausal women diagnostic process and treatment of premenopausal osteoporosis in young women reamin poorly defined. A low bone mineral density in premenopausal women is not associated with the same risk of fractures as in postmenopausal women, therefore diagnosis requires not only densitometric examination but depends on the consideration of other risk factors. Most cases of premenopausal osteoporosis are associated with chronic diseases affecting bone metabolism. Treatment of the underlying disease may improve bone density as well as bone quality. Rarely, a bone-specific antiporotic therapy may be used, although quality evidence is scarce. This article will review current opinion on definition, diagnosis and treatment of premenopausal osteoporosis.

Keywords:

premenopausal osteoporosis – risk of fracture – densitometry – treatment


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