HevyLite™ – A new method for detection of monoclonal immunoglobulins – editorial


Authors: Jakub Radocha
Authors‘ workplace: IV. interní hematologická klinika LF UK a FN Hradec Králové, přednosta doc. MUDr. Pavel Žák, Ph. D.
Published in: Vnitř Lék 2015; 61(1): 13-14
Category: Editorials


Sources

1. Bradwell AR, Carr-Smith HR, Mead GP et al. Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine. Clin Chem 2001; 47(4): 673–680.

2. Bradwell AR, Harding SJ, Fourrier NJ et al. Assessment of monoclonal gammopathies by nephelometric measurement of individual immunoglobulin kappa/lambda ratios. Clin Chem 2009; 55(9): 1646–1655.

3. Boyle EM, Fouquet G, Guidez S et al. IgA kappa/IgA lambda heavy/light chain assessment in the management of patients with IgA myeloma. Cancer 2014; 120(24): 3952–3957.

4. Koulieris E, Panayiotidis P, Harding SJ et al. Ratio of involved/uninvolved immunoglobulin quantification by HevyliteTM assay: clinical and prognostic impact in multiple myeloma. Exp Hematol Oncol 2012; 1(1): 9. Dostupné z: DOI: <http://doi:10.1186/2162–3619–1-9 >.

5. Bradwell AR, Harding SJ, Fourrier N et al. Prognostic utility of intact immunoglobulin Ig’κ/Ig’λ ratios in multiple myeloma patients. Leukemia 2013; 27(1): 202–207.

6. Katzmann JA, Clark R, Kyle RA et al. Suppression of uninvolved immunoglobulins defined by heavy/light chain pair suppression is a risk factor for progression of MGUS. Leukemia 2013; 27(1): 208–212.

7. Paiva B, Martinez-Lopez J, Vidriales MB et al. Comparison of immunofixation, serum free light chain, and immunophenotyping for response evaluation and prognostication in multiple myeloma. J Clin Oncol 2011; 29(12): 1627–1633.

8. Ludwig H, Miloslavljevic D, Zojer N et al. Immunoglobulin heavy/light chain ratios improve paraprotein detection and monitoring, identify residual disease and correlate with survival in multiple myeloma patients. Leukemia 2013; 27(1): 213–219.

9. Ščudla V, Pika T, Minařík J. Význam vyšetření párů těžkých/lehkých řetězců imunoglobulinu u monoklonálních gamapatií. Vnitř Lék 2015; 61(1): 59–70.

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Diabetology Endocrinology Internal medicine

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