Management of stable angina pectoris and of other chronic cardiovascular arterial diseases


Authors: P. Gavornik ;  A. Dukát ;  Ľ. Gašpar
Authors‘ workplace: II. interná klinika Lekárskej fakulty UK a UN Bratislava, Prvé angiologické pracovisko (PAP), Slovenská republika, prednosta prof. MUDr. Ľudovít Gašpar, CSc.
Published in: Vnitř Lék 2012; 58(7 a 8): 29-36
Category: 80th Birthday MUDr. Miroslav Mydlík, DrSc.

Overview

The aim of this document of the Angiologists’ Section of the Slovak Medical Chamber (AS SMC) is to address a member stu­dies on stable angina pectoris published in the last 5 years in order to assess their contribution to our expanding knowledge of chronic cardiovascular arterial diseases. The prevalence of angina pectoris, according to the European Society of Cardiology (ESC), is from 2–5% (men, 45–54 years-old) to 10–20% (men, 65–74 years-old) and from 0,1–1% (women, 45–54 years-old) to 10–15% (women, 65–74 years-old). During the last decade there has been a shift of these patients to a higher age group. As a result of the increased age of Europeans there is a global increase of prevalence of stable angina pectoris. This vascular illness influences mainly the quality of the patient’s life, morbidity, premature invalidity and mortality. The authors have analysed the clinical-etiology-anatomy-pathophysiology problems in patients with stable angina pectoris: lack of satisfactory pharmacotherapy, persistence of angina symptoms after revascularization, impossible revascularization in some patients, and also the poor tolerance of pharmacotherapy in others. They have focused attention mainly on treatment strategies influencing the prognosis of the patient (antithrombotics, beta-blockers, statins, ACE inhibitors) and the quality of life (calcium channel blockers, nitrates, nicorandil, trimetazidine, ranolazine, ivabradine etc.). Non-pharmacotherapy should not be forgotten, either. It is useful for the prevention of progression of cardiovascular arterial disease to diagnose it and to start early the treatment of angina pectoris. In this way we may improve the patient‘s prognosis and quality of life.

Key words:
stable angina pectoris – chronic cardiovascular arterial diseases – organovascular arterial diseases – management


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