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Immune thrombocytopaenia, diagnosis, classification, differential diagnosis


Authors: L. Červinek
Authors‘ workplace: Interní hematoonkologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Jiří Vorlíček, CSc.
Published in: Vnitř Lék 2010; 56(Supplementum 1): 75-77
Category: 16th Parizek's Days, Ostrava-Poruba, March 25th –26th 2010

Overview

Immune thrombocytopaenia (ITP) is classified among autoimmune disease. Recently, new recommendations regarding standardization of terminology, diagnostic investigations and treatment modalities have been issued. Detailed history, physical assessment and manual blood count are the main pillars of ITP diagnosis. To exclude secondary immune thrombocytopaenia, the dia­gnostics should, in selected groups of patients, include serologic determination of infections or of autoimmune or lymphoproliferative diseases.

Key words:
immune thrombocytopaenia – classification of diseases – diagnosis – differential diagnosis – secondary thrombocytopaenia


Sources

1. Provan D et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood 2010; 115: 168–186.

2. Rodeghiero F, Stasi R. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood 2009; 113: 2386–2393.

3. Ruggeri M, Fortuna S, Rodeghiero F. Heterogeneity of terminology and clinical definitions in adult idiopathic thrombocytopenic purpura: a critical appraisal from a systematic review of the literature. Haematologica 2008; 93: 98–103.

4. George JN, Woolf SH, Raskob GE et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods of American Society of Hematology. Blood 1996; 88: 3–40.

5. British Committee for Standard in Haematology General Haematology Task Force Guidelines for the investigation and management of idiopathic thrombocytopenic purpura (ITP) in adults, children and in pregnancy. Br J Haematol 2003; 120: 574–596.

6. Liebman H. Other Immune Thrombocytopenias. Semin Hematol 2007; 44 (Suppl 5): S24–S34.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue Supplementum 1

2010 Issue Supplementum 1

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