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Metabolic importance of muscles and the role of sports in diabetic patients
Authors: Š. Svačina
Authors‘ workplace: III. interní klinika 1. lékařské fakulty UK a VFN, Praha, přednosta prof. MUDr. Štěpán Svačina, DrSc., MBA
Published in: Vnitř Lék 2007; 53(5): 545-547
Category:
Overview
Muscle is a very important tissue in pathogenesis of diabetes and its complications. In future muscle will become a target of novel farmacotherapy of diabetes. Sport in diabetes has important cardiovascular effects and limited metabolic effects. Physical activity in diabetes can induce hypo - and hyperglyceaemia. Dosing scheme for insulin and diet was published for sporting in diabetes. Most important is individual selfmonitoring and adjustment of therapy during sporting activities.
Key words:
insulin therapy during sporting – diet therapy during sporting – effect of sport in diabetes – future of diabetes pharmacotherapy – future drugs influencing muscle in diabetes
Sources
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2. Haluzík M. Svačina Š. Metabolický syndrom a jaderné receptory PPAR. Praha: Grada 2006.
3. Hojlund K, Frystyk J, Levin K et al. Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes. Diabetologia 2006; 49 : 1283-1291.
4. Kim JK, Michael MD, Previs SF et al. Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle. Clin Invest 2000; 105 : 1791-1797.
5. Maugham RJ, Burke LM. Výživa ve sportu. Praha: Galén 2002.
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Labels
Diabetology Endocrinology Internal medicine
Article was published inInternal Medicine
2007 Issue 5-
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