#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Non-alcoholic fatty liver disease in cohort of patients undergoing bariatric surgery in Military University Hospital Prague


Authors: M. Paldusová 1;  P. Hříbek 1;  M. Kasalický 2;  P. Urbánek 1
Authors‘ workplace: Interní klinika 1. LF UK a ÚVN, Praha, Přednosta: prof. MUDr. Miroslav Zavoral, Ph. D. 1;  Chirurgická klinika 2. LF UK a ÚVN, Praha, přednosta: prof. MUDr. Miroslav Ryska, CSc. 2
Published in: Prakt. Lék. 2019; 99(5): 205-209
Category: Of different specialties

Overview

The worldwide prevalence of obesity is increasing in the long term. This is closely related to the increase in comorbidities. With obesity and more broadly with metabolic syndrome is associated non-alcoholic fatty liver disease. Bariatric surgery is effective way of treatment of obesity, which is conservatively difficult to treat. The goal of our study was the retrospective evaluation of the presence of nonalcoholic fatty liver disease and liver fibrosis in cohort of patients undergoing sleeve gastrectomy for class III obesity at the Department of Surgery, Military University Hospital Prague and they are followed up at the Department of Internal Medicine, Military University Hospital Prague. Using non-invasive methods, liver steatosis has been reported at the majority of patients, however advanced fibrosis was not detected in our cohort. Obesity is severe health problem. Non-alcoholic fatty liver disease is nearly obvious in these patients and is highly overlooked.

Keywords:

obesity – sleeve gastrectomy – non-alcoholic fatty liver disease – liver fibrosis


Sources

1. Češka R, Štulc T, Tesař V, Lukáš M. (eds.) Interna. 2. aktualizované vydání. Praha: Triton 2015.

2. Yumuk V, Tsigos C, Fried M, et al. European guidelines for obesity management in adults. Obesity Facts 2015; 8(6): 402–424. Dostupné z: https://www.karger.com/Article/FullText/442721 [cit. 2019-06-28].

3. World Health Organization (WHO). Obesity and overweight. 2018 (on-line). Dostupné z: https://www.who.int/en/news-room/fact-sheets/detail/obesity-and-overweight [cit. 2019-06-28].

4. Fried M, Svačina Š, a kol. Moderní trendy v léčbě obezity a diabetu. Mlečice: Axonite CZ 2018.

5. Hainer V. Základy klinické obezitologie. Praha: Grada Publishing 2004.

6. Durrer Schutz D, Busetto L, Dicker D, et al. European practical and patient-centred guidelines for adult obesity management in primary care. Obesity Facts 2019; 12(1): 40–66. Dostupné z: https://www.karger.com/Article/FullText/496183 [cit. 2019-06-28].

7. Busetto L, Dicker D, Azran C, et al. Practical recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the post-bariatric surgery medical management. Obesity Facts 2018; 10(6): 597–632. Dostupné z: https://www.karger.com/Article/FullText/481825 [cit. 2019-06-28].

8. Herlesová J, Slabá Š. Psychologické aspekty chirurgické léčby obezity. Gastroent Hepatol 2018; 72(6): 501–507.

9. Adams LA, Angulo P, Lindor KD. Nonalcoholic fatty liver disease. CMAJ 2005; 172(7): 899–905. Dostupné z: http://www.cmaj.ca/cgi/doi/10.1503/cmaj.045232 [cit. 2019-06-28].

10. Brunt EM, Janney CG, Bisceglie AM, et al. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999; 94(9): 2467–2474.

11. Schuppan D, Schattenberg JM. Non-alcoholic steatohepatitis: Pathogenesis and novel therapeutic approaches. J Gastroenterol Hepatol 2013; 28(Suppl 1): 68–76. Dostupné z: http://doi.wiley.com/10.1111/jgh.12212 [cit. 2019-06-28].

12. Ong JP, Elariny H, Collantes R, et al. Predictors of nonalcoholic steatohepatitis and advanced fibrosis in morbidly obese patients. Obes Surg 2005; 15(3): 310–315.

13. Machado M, Marques-Vidal P, Cortez-Pinto H. Hepatic histology in obese patients undergoing bariatric surgery. J Hepatol 2006; 45(4): 600–606.

14. Souto KP, Meinhardt NG, Ramos MJ, et al. Nonalcoholic fatty liver disease in patients with different baseline glucose status undergoing bariatric surgery: analysis of intraoperative liver biopsies and literature review. Surg Obes Relat Dis 2018; 14(1): 66–73.

15. Wai CT, Greenson JK, Fontana RJ, et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C Hepatology 2003; 38(2): 518–526.

16. Sterling RK, Lissen E, Clumeck N, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology 2006; 43(6): 1317–1325.

17. Forns X, Ampurdanès S, Llovet JM, et al. Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model. Hepatology 2002; 36(4): 986–992.

18. Koda M, Matunaga Y, Kawakami M, et al. Fibroindex, a practical index for predicting significant fibrosis in patients with chronic hepatitis C Hepatology 2007; 45(2): 297–306.

19. Perrone F, Bianciardi E, Benavoli D, et al. Gender influence on long-term weight loss and comorbidities after laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass: a prospective study with a 5-year follow-up. Obes Surg 2016; 26(2): 276–281.

20. Berducci MA, Nefa J, Gallo A, et al. Gender influence in bariatric surgery outcomes: sleeve gastrectomy and gastric bypass (online). Dostupné z: https://www.sages.org/meetings/annual-meeting/abstracts-archive/gender-influence-in-bariatric-surgery-outcomes-sleeve-gastrectomy-and-gastric-bypass/ [cit. 2019-07-12].

21. Kochkodan J, Telem DA, Ghaferi AA. Physiologic and psychological gender differences in bariatric surgery. Surg Endosc 2018; 32(3): 1382–1388.

22. Grilo CM, Masheb RM, Brody M, et al. Binge eating and self-esteem predict body image dissatisfaction among obese men and women seeking bariatric surgery. Int J Eat Disord 2005; 37(4): 347–351.

23. Koula M, Hrůzová M, Harmáček D, a kol. Metody neinvazivního stanovení pokročilosti jaterní fibrózy. Gastroent Hepatol 2016; 70(2): 118–124.

24. Shah AG, Lydecker A, Murray K, et al. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2009; 7(10): 1104–1112.

25. Brolin RE, Bradley LJ, Taliwal RV. Unsuspected cirrhosis discovered during elective obesity operations. Arch Surg 1998; 133(1): 84–88.

26. RadiologyPics.com. Fatty liver disease – ultrasound (online). Dostupné z: https://radiologypics.com/2013/02/08/fatty-liver-disease-ultrasound/ [cit. 2019-07-12].

27. Saadeh S, Younossi ZM, Remer EM, et al. The utility of radiological imaging in nonalcoholic fatty liver disease. Gastroenterology 2002; 123(3): 745–750 [cit. 2019-04-07]. doi:10.1053/gast.2002.35354. ISSN 00165085. Dostupné z: http://linkinghub.elsevier.com/retrieve/pii/S001650850200166X

28. Lee SS, Park SH. Radiologic evaluation of nonalcoholic fatty liver disease. World Journal of Gastroenterology (online) 2014; 20(23): 7392–7402 [cit. 2019-04-07]. doi:10.1016/j.jhep.2010.01.008. ISSN 1007-9327. Dostupné z: http://www.wjgnet.com/1007-9327/full/v20/i23/7392.htm

29. Yersiz H, Lee C, Kaldas FM, et al. Assessment of hepatic steatosis by transplant surgeon and expert pathologist: A prospective, double-blind evaluation of 201 donor livers. Liver Transplantation (online) 2013; 19(4): 437–449 [cit. 2019-04-07]. doi:10.1002/lt.23615. ISSN 15276465. Dostupné z: http://doi.wiley.com/10.1002/lt.23615

Labels
General practitioner for children and adolescents General practitioner for adults
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#