Actinic prurigo
Authors:
L. Malina
Authors‘ workplace:
Mediscan Group, Praha
Published in:
Prakt. Lék. 2009; 89(4): 196-198
Category:
Of different specialties
Overview
Actinic (solar) prurigo is mostly likely an idiopathic disease, which should be principally differentiated from a similar pruriginous form of chronic polymorphous photodermatosis. The diversity of both the diseases is based not only on the dissimilarity of clinical symptoms and/or on the reaction to UV-radiation, but particularly on the different characteristic results of their HLA-phenotype immunoassay. Drugs used as standard for the treatment of serious forms of photodermatoses have no proven significant favourable effects for the present. Only high-risk systemic administration of the immunosupressive thalidomide seems to be successful in these disease-cases.
Key words:
photodermatoses, actinic prurigo, HLA-typization, MHC class II gene DRB, action spectra UVA, UVB, photoantigenes, immunology of photodermatoses, thalidomide.
Sources
1. Grabczynska, S.A., McGregor, J.M., Kondeatis, E. et al. Actinic prurigo and polymorphic light eruption: common pathogenesis and the importance of HLA-DR4/DRBl*0407. Br. J. Dermatol. 1999,140, p. 232-236.
2. Worret, W-I., Vocks, E., Frias, G. et al. Aktinische Prurigo. Hautarzt 2000, 51, p. 474-478.
3. Calnan, C.D., Meara, R.H. Actinic prurigo. Clin. Exp. Dermatol. 1977, 2, p. 365.
4. Epstein, J.H. Polymorphous light eruption. J. Am. Acad. Dermatol. 1980, 3, p. 329-343.
5. Hölzle, E., Rowold, J., Plewig G. Aktinische Prurigo. Hautarzt 1992, 43, p. 278-282.
6. Magnus, I.A. Prurigo aestivale. In:Dermatological Photobiology. Oxford: Blackwell, 1976, p. 174-175.
7. Lim, H.W., Epstein, J.H. Photosensitivity diseases. J. Am. Acad. Dermatol. 1997, 1, p. 84-90.
8. Malina, L. Aktinické prurigo. In: Fotodermatózy. Praha: Maxdorf, 2. vyd., 2005, s. 65-68.
9. Hojyo-Tomoka, T., Vega-Memije, E., Granados, J. et al. Actinic prurigo: an update. Int. J. Dermatol. 1995, 34, p. 380-384.
10. Menage, H.P., Vaughan, R.W., Baker, C.S. et al. HLA-DR4 may determine expression of actinic prurigo in British patients. J. Invest. Dermatol. 1996, 106, p. 362-364.
11. Fusaro, R.M., Johnson, J.A. Hereditary polymorphic light eruption of American Indians: occurence in non-indians with polymorphic light eruption. J. Am .Acad. Dermatol. 1996, 34, p. 612-617.
12. Addo, H.A., Frain-Bell, W. Actinic prurigo − a specific photodermatosis? Photodermatology 1984, 1, p. 119-128.
13. Johnson, J A., Fusaro, R M. Photosensitivity of the American Indian: terminology and historical aspects. J. Am. Acad. Dermatol. 1998, 39, p..662-663.
14. Hojyo-Tomoka, M.T., Vega-Memije, M.E., Cortes-Franco, R. et al. Diagnosis and treatment of actinic prurigo. Dermatol. Ther. 2003, 16, p. 40-44.
15. Frain-Bell W. Actinic prurigo. In: Cutaneous Photobiology. Oxford: Oxford Univ. Press, 1985, p. 39-46.
16. Lane, P.R., Hogan, D.J., Martel, M.J. et al. Actinic prurigo: clinical features and prognosis. J. Am. Acad. Dermatol. 1992, 26, p. 683-692.
17. Jansen, C.T. Heredity of chronic polymorphous light eruption. Arch. Dermatol. 1978, 114, p. 188-190.
18. O’Reilly, F.M., Spencer, S., Derke, C. et al. HLA-DR4B1*0407 − strong association with actinic prurigo in Ireland. Br. J. Dermatol. 1996, 135 (Suppl. 47), p. 65 (Abstr.).
19. Lane, P.R., Sheridan, D.P., Hogan, D.J. et al. HLA typing in polymorphous light eruption. J. Am. Acad. Dermatol. 1991, 4, p. 570-573.
20. Malina, L. Chronická aktinická dermatida a její společný výskyt s dalšími idiopatickými fotodermatózami. Med po prom. 2009, v tisku.
21. Londoňo, F. Thalidomide in the treatment of actinic prurigo. Int. J. Dermatol. 1973,12, p. 326-328.
22. Hawk, J.L.M. Benign summer light eruption and polymorphic light eruption: genetic and functional studies suggest that a revised nomenclature is required. J. Cosmet. Dermatol. 2004, 3, p. 173-175.
23. Malina, L. Chronická polymorfní fotodermatóza. Postgrad. med. 2008, 10, p. 854-856.
24. Krutmann, J. Immunologische Mechanismen von Photodermatosen. Akt. Dermatol. 1995, 21, p. 376-378.
25. Moncada, B., Gonzales-Amaro, R., Baranda, L. Immunopathology of polymorphous light eruption. J. Am. Acad. Dermatol. 1984, 10, p. 970-973.
26. Gonzales, E., Gonzales, S. Drug sensitivity, idiopathic photodermatoses, and sunscreens. J. Am. Acad. Dermatol. 1996, 35, p. 871-875.
27. Farr, P.M., Diffey, B.L. Augmentation of ultraviolet erythema by indomethacin in actinic prurigo: evidence of mechanism of photosensitivity. Photochem. Photobiol. 1989, 47, p. 413-417.
28. Megahed, M., Schaller, J. Histopathologie der Photodermatosen. Hautarzt 2006, 12, p. 1083-1088.
29. Jong, C.T., Finlay, A.Y., Pearse, A.D. et al. The quality of life of 790 patients with photodermatoses. Br. J. Dermatol. 2008, 159, p. 192-197.
30. Millard, T.P, Bataille, V., Snieder, H. et al. The heritability of polymorphic light eruption. J. Invest. Dermatol. 2000, 115, s. 467-470.
31. Estrada, G.I., Garibay-Escobar, A., Nuňes-Vázquez, A. et al. Evidence that thalidomide modifies the immune response of patients suffering from actinic prurigo. Int. J. Dermatol. 2004, 43, p. 893-897.
32. Ross, G., Foley, P., Baker, C. Actinic prurigo. Photodermatol. Photoimmunol. Photomed. 2008, 24, p. 272-275.
33. Virtaranta-Knowles, K., Sistonen, P., Nivanlinna, H.R. A population genetic study in Finland: comparison of the Finnish- and Swedish-speaking population. Hum. Hered. 1991, 41, p. 248-264.
34. Perret, C.M., Harwood, C.A., Khorshid, M. et al. Primary cutaneous B-cell lymphoma associated with actinic prurigo. Br. J. Dermatol. 2005, 153, p. 186-189.
35. Kölgen, W. Differential expression of cytokines in UV-B- exposed skin of patients with polymorphous light eruption: Correlation with Langerhans cell migration and immunosuppression. Arch. Dermatol. 2004,140, p. 295-305.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2009 Issue 4
Most read in this issue
- Lichen sclerosus
- Detection of latent tuberculosis, QuantiFERON-TB Gold test, possibilities and pitfalls of the method
- Microvascular decompression of cranial nerves – effect and risk of treatment
- Current overview of the diagnosis and treatment of cancer of the stomach