Tuberculosis – still a health problem
Authors:
P. Čermák 1; M. Havelková 2
Authors‘ workplace:
Fakultní Thomayerova nemocnice s poliklinikou, Praha
Oddělení klinické mikrobiologie
Primář: doc. MUDr. Pavel Čermák, CSc.
1. lékařská fakulta Univerzity Karlovy v Praze
Ústav klinické biochemie a laboratorní diagnostiky
Přednosta: prof. MUDr. Tomáš Zima,
1; Státní zdravotní ústav, Praha
Národní referenční laboratoř pro mykobakterie
Ředitel: MUDr. Milan Bořek
2
Published in:
Prakt. Lék. 2009; 89(12): 692-697
Category:
Diagnostis
Overview
Tuberculosis is still a major health problem, especially in developing countries. Nearly 2 million people die from tuberculosis each year. Extremely drug-resistant and multidrug-resistant tuberculosis strains present serious problems for the efficient control of this disease. Conventional methods for the identification of M. tuberculosis and detection of drug-resistance are slow and cumbersome. Determination of the genome sequence of M. tuberculosis has facilitated the development of new molecular assays. These new methods can be performed rapidly and offer high sensitivities and specificities. They can also be used for the detection of drug resistance. This review describes the current possibilities for the laboratory diagnosis of tuberculosis.
Key words:
tuberculosis, laboratory diagnosis, interferon gamma.
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