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Acute toxic hepatitis following consumption of a herbal preparation
Authors: I. Hejlová 1; J. Šperl 1; S. Fraňková 1; D. Kamenář 1; E. Sticová 2; J. Špičák 1
Authors‘ workplace: Klinika hepatogastroenterologie Přednosta: prof. MUDr. Julius Špičák, CSc. ; Pracoviště klinické a transplantační patologie Přednosta: MUDr. Eva Honsová, Ph. D. Institut klinické a experimentální medicíny, Praha Ředitel: doc. MUDr. Jan Malý, CSc. 2
Published in: Prakt. Lék. 2008; 88(2): 108-110
Category: Case Report
Overview
Acute toxic hepatitis can be induced by a range of drugs, it can also occur after the consumption of herbal preparations. We present a case of acute toxic hepatitis following the use of a herbal food supplement for the treatment of psoriasis. It is widely recognised that conventional medications can give rise to serious adverse reactions, but this is also true of herbal preparations even though they are generally considered to be harmless by the lay public.
Keywords:
hepatotoxicity, herbal preparation.
Sources
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2. Elinav, E., Pinsker, G., Safadi, R. et al. Association between consumption of Herbalife nutritional suplements and acute hepatotoxicity. J. Hepatol. 2007, 47, p. 514-520.
3. Ioannides, C. Pharmacokinetic interactions between herbal remedies and medicinal drugs. Xenobiotika 2002, 32, p. 451-478.
4. Kasper, H-U., Drebber, U., Hirsch, I., Dienes, H.P. Morphologische Veränderungen der medikamenteninduzierten Leberschädigung. Pathologe. 2006, 27, s. 175-181.
5. Pak, E., Esrason, T., Wu, Victor H. Hepatotoxicity of herbal remedies: an emerging dilemma. Prog. Transplant. 2004, 14, p. 91-96.
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7. Shad, J.A, Chinn, C.G., Brann, O.S. Acute hepatitis after ingestion of herbs. South Med. J. 1999, 92, p. 1095-1097.
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9. Stickel, F., Egerer, G., Seitz, H.K. Hepatotoxicity of botanicals. Public Health Nutrition 2000, 3, p. 113-124.
10. Stickel, F., Patsenker, E., Schuppan, D. Herbal hepatotoxicity. J. Hepatol. 2005, 43, p. 901-910.
11. Willett, K.L., Roth, R.A., Walker, L. Hepatotoxicity assesment for botanical dietary supplements. Toxicol. Sci. 2004, 79, p. 4-9.
12. Benichou, C. Criteria of drug-induced liver disorders. Report of an International consensus meeting. J. Hepatol.1990, 11, p. 272-276
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General practitioner for children and adolescents General practitioner for adults
Article was published inGeneral Practitioner
2008 Issue 2-
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