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Current options for active immunization of HIV infected patients


Authors: D. Jilich 1,2;  L. Machala 1;  M. Staňková 2
Authors‘ workplace: Univerzita Karlova, Praha 1. lékařská fakulta ;  Klinika infekčních nemocí, FN Na Bulovce, Praha Primářka: MUDr. Hana Roháčová, Ph. D. 1;  III. klinika infekčních a tropických nemocí Přednosta: doc. MUDr. Michal Holub, Ph. D. 2
Published in: Prakt. Lék. 2008; 88(11): 649-651
Category: Of different specialties

Overview

Due to their immunodeficiency, HIV positive patients are at greater risk from many infections, including the preventable ones. Vaccination is the most effective means of protection. However the physician’s attitude to the vaccination of immunocompromised patients needs to be very specific. The effectiveness of vaccination correlates strongly with actual immunological status. The use of live vaccines is mostly not indicated because of the potentional risk. Vaccination is relatively safe, including some live vaccines, in persons with CD4+ T cells > 500/μμl.

Key words:
HIV, prevention, vaccination, safety, efficacy.


Sources

1. Albrecht, D., Weitzel, T. Vaccinations and HIV. In: Hoffmann C, Rockstroh J, Kamps B, eds. HIV Medicine. Paris, Cagliari, Wuppertal: Flying Publisher, 2007.

2. Armenian, S., Han, J., Dunaway, T. et al. Safety and immunogenicity of live varicella virus vaccine in children with human immunodeficiency virus type 1. Pediatr. Infect. Dis. J. 2006, 4, p. 368-370.

3. Bartlett, J., Gallant, J. Medical management of HIV infection. Baltimore: John Hopkins Medicine Health Publishing Business Group, 2004.

4. Geretti, A., Brook, G., Cameron, C. et al. British HIV Association Immunisation Subcommittee: Immunisation Guidelines for HIV-infected Adults. Dostupné na http://www.bhiva.org/files/file1001634.pdf. Accessed January 15, 2008.

5. Gonzalez, B., Moreno, S., Burdach, R. et al. Clinical presentation of Bacillus Calmette-Guérin infections in patients with immunodeficiency syndromes. Pediatr. Infect. Dis. 1989, 8, p. 201-206.

6. Jilich, D., Machala, L., Stankova, M. et al. Proposals for guidelines for vaccination of adults infected with HIV-1 in the Czech Republic. Clin. Inf. Micro. J. 2008, 14(2), p. 59-64.

7. Jordano, Q., Falcó, V., Almirante, B. et al. Invasive pneumococcal disease in patients infected with HIV: still a threat in the era of highly active antiretroviral therapy. Clin. Infect. Dis. 2004, 38, p. 1623-1628.

8. Kengusakul, K., Sathirapongsasuti, K., Punyagupta, S. Fatal myeloencephalitis following yellow fever vaccination in a case with HIV infection. J. Med. Assoc. Thai. 2002, 85, p. 131-134.

9. Klein, M., Lu, Y., DelBalso, L. et al. Influenzavirus infection is a primary cause of febrile respiratory illness in HIV-infected adults, despite vaccination. Clin. Infect. Dis. 2007, 54, p. 234-240.

10. Lange, C., Lederman, M., Medvik, K. et al. Nadir CD4+ T-cell count and numbers of CD28+ CD4+ T-cells predict functional responses to immunizations in chronic HIV-1 infection. AIDS 2003, 17, p. 2015-2023.

11. Kolber, M., Gabr, A., De La Rosa, A. et al. Genotypic analysis of plasma HIV-1 RNA after influenza vaccination of patients with previously undetectable viral load. AIDS 2002, 16, p. 537-542.

12. Moss, J., Scott, S., Mugala, N. et al. Immunogenicity od standard-titer measles vaccine in HIV-1-infected und uninfected Zambian children: an observational study. J. Infect. Dis. 2007, 196, p. 347-355.

13. Mofenson, L., Oleske, J., Serchuck, L. et al. Treating opportunistic infections among HIV-exposed and infected children: recommendations from CDC, the National Institutes of Health, and the Infectious Diseases Society of America. Clin. Infect. Dis. 2005, 40, p. 410-416.

14. Penaranda, M., Falco, V., Payeras, A. et al. Effectiveness of polysaccharide pneumococcal vaccine in HIV-infected patients: a case-control study. Clin. Infect. Dis. 2007, 45, e82-87.

15. Rousseau, M., Moreau, J., Delmont, J. Vaccination and HIV: a review of the literature. Vaccine 2000, 18, p. 825-831.

16. Spach, D. Immunizations for HIV-infected adults: indications, timing, and response. Top HIV Med. 2006, 14, p. 154-158.

Labels
General practitioner for children and adolescents General practitioner for adults
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