Symptoms of paraneoplastic encephalopathy as the first clinical sign of Hodgkin’s lymphoma. A case study


Authors: Z. Rusiňáková;  L. Raida;  K. Indrák
Authors‘ workplace: Hemato-onkologická klinika LF UK Palackého a Fakultní nemocnice Olomouc ;  Prednosta: Prof. MUDr. Karel Indrák, DrSc.
Published in: Prakt. Lék. 2007; 87(2): 114-116
Category: Case Report

Overview

Limbic encephalopathy and subacute cerebellar degeneration are rare paraneoplastic autoimmune epiphenomena associated with Hodgkin’s lymphoma. Only a few cases have been reported in the literature. This report describes the case of a 19 year old female, whose neurological symptoms resulted from a paraneoplastic encephalopathy and became one of the first and dominant clinical manifestations of Hodgkin’s lymphoma. Diagnosis of paraneoplastic encephalopathy was concluded after exclusion of neuroinfection, primary demyelinating disease of the central nervous system and it was based on complete neurological restoration, followed by remission of lymphogranuloma achieved by combined chemotherapy in primary treatment.

Key words:
Hodgkin’s lymphoma, encephalopathy, central nervous system, autoimmunity, therapeutic response.


Labels
General practitioner for children and adolescents General practitioner for adults
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

×