Authors: P. Jandík 1; J. Mergancová 1; F. Čečka 1; B. Melichar 2; J. Dvořák 2; H. Urmínská 3 Authors‘ workplace: Chirurgická klinika přednosta prof. MUDr. Zbyněk Vobořil, DrSc. 1; Klinika onkologie a radioterapie přednosta doc. MUDr. Jiří Petera, Ph. D. 2; Radiodiagnostická klinika přednosta prof. MUDr. Pavel Eliáš, CSc. Fakultní nemocnice Hradec Králové Ředitel: doc. MUDr. Leoš Heger, CSc. 3 Published in: Prakt. Lék. 2006; 86(6): 333-335 Category: Of different specialties
The authors presents a group of 52 patients in advanced age with non-metastatic breast cancer. In addition to confirmed hormonally dependent carcinoma, all have had an important co-morbidity. Therefore in all patients, hormonal therapy (HT) by selective aromatase inhibitors was the first choice treatment. Tumor regression was detected in 45 patients (86, 5%), a complete clinical response in 8 (15,5 %). An important therapeutic benefit was noticed, which helped to maintain an adequate quality of life.
Key words: breast carcinoma in the elderly, selective aromatase inhibitors, primary treatment
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