Authors: K. Trnavský Authors‘ workplace: IPVZ a Arthrocentrum, Praha Published in: Prakt. Lék. 2005; 85(3): 157-159 Category: Therapy
Research in new substances with analgetic and anti-inflammatory effects continues. Sought for are therapeutics with a minimum of side-effects because in question is usually long-term treatment. Nimesulid is one of such drugs, being classified among the so-called preferential non-steroid anti-rheumatics (it has certain properties of non-selective non-steroid antirheumatics and simultaneously a preferential inhibitory activity towards cyclo-oxygenase-2) with a minimum of undesirable effects as to the digestive tract. The hepatotoxicity of nimesulid is no different from hitherto applied non-steroid antirheumatics.
Key words: rheumatic disease – analgetic therapy – non-steroid antirheumatics.
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