Authors: H. Kraus Authors‘ workplace: Oční klinika 1. LF UK a VFN, Praha, přednosta doc. MUDr. M. Filipec, CSc. Published in: Prakt. Lék. 2003; (11): 625-626 Category:
Elevated intraocular pressure, the most important risk factor, was discussed in the first part ofthe paper. The influence of older age was identified as a strong supportive risk factor in severalstudies, as well as racial factors. A higher prevalence of primary open-angle glaucoma in blackswas found in population based studies. Family history plays an important role in the developmentof glaucoma. In recent years, 6 genes for primary open-angle glaucoma have beenidentified. In some epidemiological studies, myopia has been found to be a factor of mediumsignificance. Neurotoxicity causes death by apoptosis of the retinal ganglion cells in the opticnerve and the retina. Neuroprotection is a promising potential therapy in glaucoma, however,none of the drugs used to treat glaucoma has any neuroprotective effect in humans.
Key words: glaucoma - risk factors - family incidence - myopia - neurotoxicity.
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