Lithium, Valproate and Carbamazepine in the Treatment of Bipolar Afective Disorders during Pregnancy and the Postdelivery Period
Authors:
M. Bareš; L. Linhartová
Authors‘ workplace:
Psychiatrické centrum Praha, ředitel prof. MUDr. C. Hóschl, DrSc. 3. LF UK Praha, děkan prof. MUDr. M. Anděl, DrSc.
Published in:
Prakt. Lék. 2001; (11): 645-648
Category:
Overview
In the introduction the authors characterize briefly bipolar affective disorders. They discuss the course of bipolar affective disorders during pregnancy and after delivery, characterized by an increased risk of rekurence and relapse of complaints. In the main part the authors review the contemporary literatury on the use of lithium, karbamazepin, valproate in the treatment of bipolar disorders during the mentioned periods and characterize the main assets and risks of their use (teratogenicity, perinatal toxicity, undesirable effects during breastfeeding, behavioural teratogenicity etc.). In the conclusion the authors present the algorithm of treatment of bipolar disorders during pregnancy and after delivery focused on the mentioned pharmaceutical preparations.
Key words:
bipolar affective disorder - pregnancy - postpartum period - lactation - lithium - valproate - carbamazepine - teratogenicity - perinatal toxicity - behavioural teratogenicity.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2001 Issue 11
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