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Lipophilic Yeasts of the Genus Malassezia and Skin Diseases.II. Atopic Dermatitis


Authors: D. Buchvald
Authors‘ workplace: Detská dermatovenerologická klinika LFUK a DFNsP, Bratislava
Published in: Epidemiol. Mikrobiol. Imunol. 59, 2010, č. 4, s. 197-204

Overview

Malassezia yeasts have the capability to modulate the immune response directed against them in opposite ways. They are capable to evade the recognition by, or suppress the response of, the immune system and live on the skin surface as commensals. On the other hand, they may elicit an inflammatory response leading to tissue injury and to the development or maintenance of inflammatory skin lesions. Approximately half of the patients with atopic dermatitis have demonstrable hypersensitivity to various allergens of Malassezia yeasts and these data strongly support the assumption that lipophilic yeasts may contribute to the exacerbations of atopic dermatitis lesions.

Key words:
lipophilic yeasts – immune response – hypersensitivity – atopic dermatitis.


Sources

1. Akamatsu, H., Komura, J., Asada, Y., Miyachi, Y. et al. Inhibitory effect of azelaic acid on neutrophil functions: a possible cause for its efficacy in treating pathogenetically unrelated diseases. Arch. Dermatol. Res., 1991, 283, 3, p. 162–166.

2. Andersson, A., Rasool, O., Schmidt, M., Kodzius, R. et al. Cloning, expression and characterization of two new IgE-binding proteins from the yeast Malassezia sympodialis with sequence similarities to heat shock proteins and manganese superoxide dismutase. Eur. J. Biochem., 2004, 271, 10, p. 1885–1894.

3. Ashbee, H. R. Recent developments in the immunology and biology of Malassezia species. FEMS Immunol. Med. Microbiol., 2006, 47, 1, p. 14–23.

4. Ashbee, H. R. Update on the genus Malassezia. Med. Mycol., 2007, 45, 4, p. 287–303.

5. Ashbee, H. R., Evans, E. G. Immunology of diseases associated with Malassezia species. Clin. Microbiol. Rev., 2002, 15, 1, p. 21–57.

6. Ashbee, H. R., Fruin, A., Holland, K. T., Cunliffe, W. J. et al. Humoral immunity to Malassezia furfur serovars A, B and C in patients with pityriasis versicolor, seborrheic dermatitis and controls. Exp. Dermatol., 1994, 3, 5, p. 227–233.

7. Baroni, A., Orlando, M., Donnarumma, G., Farro, P. et al. Toll-like receptor 2 (TLR2) mediates intracellular signalling in human keratinocytes in response to Malassezia furfur. Arch. Dermatol. Res., 2006, 297, 7, p. 280–288.

8. Baroni, A., Perfetto, B., Paoletti, I., Ruocco, E. et al. Malassezia furfur invasiveness in a keratinocyte cell line (HaCat): effects on cytoskeleton and on adhesion molecule and cytokine expression. Arch. Dermatol. Res., 2001, 293, 8, p. 414–419.

9. Bayrou, O., Pecquet, C., Flahault, A., Artigou, C. et al. Head and neck atopic dermatitis and Malassezia--furfur-specific IgE antibodies. Dermatology, 2005, 211, 2, p. 107–113.

10. Buentke, E., Heffler, L. C., Wallin, R. P., Lofman, C. et al. The allergenic yeast Malassezia furfur induces maturation of human dendritic cells. Clin. Exp. Allergy, 2001, 31, 10, p. 1583–1593.

11. Buentke, E., Zargari, A., Heffler, L. C., Avila-Carino, J. et al. Uptake of the yeast Malassezia furfur and its allergenic components by human immature CD1a+ dendritic cells. Clin. Exp. Allergy, 2000, 30, 12, p. 1759–1770.

12. Casagrande, B. F., Fluckiger, S., Linder, M. T., Johansson, C. et al. Sensitization to the yeast Malassezia sympodialis is specific for extrinsic and intrinsic atopic eczema. J. Invest. Dermatol., 2006, 126, 11, p. 2414–2421.

13. d’Ostiani, C. F., Del Sero, G., Bacci, A., Montagnoli, C. et al. Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo. J. Exp. Med., 2000, 191, 10, p. 1661–1674.

14. David, M., Gabriel, M., Kopecka, M. Microtubular and actin cytoskeletons and ultrastructural characteristics of the potentially pathogenic basidiomycetous yeast Malassezia pachydermatis. Cell Biol. Int., 2007, 31, 1, p. 16–23.

15. Donnarumma, G., Paoletti, I., Buommino, E., Orlando, M. et al. Malassezia furfur induces the expression of beta-defensin-2 in human keratinocytes in a protein kinase C-dependent manner. Arch. Dermatol. Res., 2004, 295, 11, p. 474–481.

16. Faggi, E., Pini, G., Campisi, E., Gargani, G. Anti-Malassezia furfur antibodies in the population. Mycoses, 1998, 41, p. 7–8, 273–275.

17. Johansson, C., Sandstrom, M. H., Bartosik, J., Sarnhult, T. et al. Atopy patch test reactions to Malassezia allergens differentiate subgroups of atopic dermatitis patients. Br. J. Dermatol., 2003, 148, 3, p. 479–488.

18. Johansson, C., Tengvall, L. M., Aalberse, R. C., Scheynius, A. Elevated levels of IgG and IgG4 to Malassezia allergens in atopic eczema patients with IgE reactivity to Malassezia. Int. Arch. Allergy. Immunol., 2004, 135, 2, p. 93–100.

19. Kato, H., Sugita, T., Ishibashi, Y., Nishikawa, A. Detection and quantification of specific IgE antibodies against eight Malassezia species in sera of patients with atopic dermatitis by using an enzyme-linked immunosorbent assay. Microbiol. Immunol., 2006, 50, 11, p. 851–856.

20. Kesavan, S., Holland, K. T., Ingham, E. The effects of lipid extraction on the immunomodulatory activity of Malassezia species in vitro. Med. Mycol., 2000, 38, 3, p. 239–247.

21. Kesavan, S., Walters, C. E., Holland, K. T., Ingham, E. The effects of Malassezia on pro-inflammatory cytokine production by human peripheral blood mononuclear cells in vitro. Med. Mycol., 1998, 36, 2, p. 97–106.

22. Khosravi, A. R., Hedayati, M. T., Mansouri, P., Shokri, H. et al. Immediate hypersensitivity to Malassezia furfur in patients with atopic dermatitis. Mycoses, 2007, 50, 4, p. 297–301.

23. Koyama, T., Kanbe, T., Ishiguro, A., Kikuchi, A. et al. Antigenic components of Malassezia species for immunoglobulin E antibodies in sera of patients with atopic dermatitis. J. Dermatol. Sci., 2001, 26, 3, p. 201–208.

24. Lange, L., Alter, N., Keller, T., Rietschel, E. Sensitization to Malassezia in infants and children with atopic dermatitis: prevalence and clinical characteristics. Allergy, 2008, 63, 4, p. 486–487.

25. Lebre, M. C., van der Aar, A. M., van Baarsen, L., van Capel, T. M. et al. Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9. J. Invest. Dermatol., 2007, 127, 2, p. 331–341.

26. Lintu, P., Savolainen, J., Kortekangas-Savolainen, O., Kalimo, K. Systemic ketoconazole is an effective treatment of atopic dermatitis with IgE-mediated hypersensitivity to yeasts. Allergy, 2001, 56, 6, p. 512–517.

27. Lopez-Garcia, B., Lee, P. H., Gallo, R. L. Expression and potential function of cathelicidin antimicrobial peptides in dermatophytosis and tinea versicolor. J. Antimicrob. Chemother., 2006, 57, 5, p. 877–882.

28. Mayser, P., Gross, A. IgE antibodies to Malassezia furfur, M. sympodialis and Pityrosporum orbiculare in patients with atopic dermatitis, seborrheic eczema or pityriasis versicolor, and identification of respective allergens. Acta Derm. Venereol., 2000, 80, 5, p. 357–361.

29. Mittag, H. Fine structural investigation of Malassezia furfur. II. The envelope of the yeast cells. Mycoses, 1995, 38, p. 1–2, 13–21.

30. Mommaas, A. M., Mulder, A. A., Jordens, R., Out, C. et al. Human epidermal Langerhans cells lack functional mannose receptors and a fully developed endosomal/lysosomal compartment for loading of HLA class II molecules. Eur. J. Immunol., 1999, 29, 2, p. 571–580.

31. Nakanishi, K., Yoshimoto, T., Tsutsui, H., Okamura, H. Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev., 2001, 12, 1, p. 53–72.

32. Nazzaro-Porro, M., Passi, S. Identification of tyrosinase inhibitors in cultures of Pityrosporum. J. Invest. Dermatol., 1978, 71, 3, p. 205–208.

33. Parry, M. E., Sharpe, G. R. Seborrhoeic dermatitis is not caused by an altered immune response to Malassezia yeast. Br. J. Dermatol., 1998, 139, 2, p. 254–263.

34. Pierard-Franchimont, C., Arrese, J. E., Pierard, G. E. Immunohistochemical aspects of the link between Malassezia ovalis and seborrheic dermatitis. J. Eur. Acad. Dermatol. Venereol., 1995, 4, 1, p. 14–19.

35. Richardson, M. D., Shankland, G. S. Enhanced phagocytosis and intracellular killing of Pityrosporum ovale by human neutrophils after exposure to ketoconazole is correlated to changes of the yeast cell surface. Mycoses, 1991, 34, p. 1–2, 29–33.

36. Rippke, F., Schreiner, V., Doering, T., Maibach, H. I. Stratum corneum pH in atopic dermatitis: impact on skin barrier function and colonization with Staphylococcus aureus. Am. J. Clin. Dermatol., 2004, 5, 4, p. 217–223.

37. Scalabrin, D. M., Bavbek, S., Perzanowski, M. S., Wilson, B. B. et al. Use of specific IgE in assessing the relevance of fungal and dust mite allergens to atopic dermatitis: a comparison with asthmatic and nonasthmatic control subjects. J. Allergy Clin. Immunol., 1999, 104, 6, p. 1273–1279.

38. Scheynius, A., Johansson, C., Buentke, E., Zargari, A. et al. Atopic eczema/dermatitis syndrome and Malassezia. Int. Arch. Allergy Immunol., 2002, 127, 3, p. 161–169.

39. Schmid-Grendelmeier, P., Fluckiger, S., Disch, R., Trautmann, A. et al. IgE-mediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis. J. Allergy Clin. Immunol., 2005, 115, 5, p. 1068–1075.

40. Schmid-Grendelmeier, P., Scheynius, A., Crameri, R. The role of sensitization to Malassezia sympodialis in atopic eczema. Chem. Immunol. Allergy, 2006, 91, p. 98–109.

41. Schneider, J. J., Unholzer, A., Schaller, M., Schafer-Korting, M. et al. Human defensins. J. Mol. Med., 2005, 83, 8, p. 587–595.

42. Selander, C., Zargari, A., Mollby, R., Rasool, O. et al. Higher pH level, corresponding to that on the skin of patients with atopic eczema, stimulates the release of Malassezia sympodialis allergens. Allergy, 2006, 61, 8, p. 1002–1008.

43. Shibata, N., Saitoh, T., Tadokoro, Y., Okawa, Y. The cell wall galactomannan antigen from Malassezia furfur and Malassezia pachydermatis contains {beta}- 1,6-linked linear galactofuranosyl residues. Microbiology, 2009, 155, 10, p. 3420–3429.

44. Steinman, R. M. Some interfaces of dendritic cell biology. APMIS, 2003, 111, p. 7–8, 675–697.

45. Suzuki, T., Ohno, N., Ohshima, Y., Yadomae, T. Soluble mannan and beta-glucan inhibit the uptake of Malassezia furfur by human monocytic cell line, THP-1. FEMS Immunol. Med. Microbiol., 1998, 21, 3, p. 223–230.

46. Tengvall Linder, M., Johansson, C., Zargari, A., Bengtsson, A. et al. Detection of Pityrosporum orbiculare reactive T cells from skin and blood in atopic dermatitis and characterization of their cytokine profiles. Clin. Exp. Allergy, 1996, 26, 11, p. 1286–1297.

47. Tengvall Linder, M., Johansson, C., Bengtsson, A., Holm, L. et al. Pityrosporum orbiculare-reactive T-cell lines in atopic dermatitis patients and healthy individuals. Scand. J. Immunol., 1998, 47, 2, p. 152–158.

48. Thomas, D. S., Ingham, E., Bojar, R. A., Holland, K. T. In vitro modulation of human keratinocyte pro- and anti-inflammatory cytokine production by the capsule of Malassezia species. FEMS Immunol. Med. Microbiol., 2008, 54, 2, p. 203–214.

49. Uchi, H., Terao, H., Koga, T., Furue, M. Cytokines and chemokines in the epidermis. J. Dermatol. Sci., 2000, 24, Suppl. 1, p. S29–S38.

50. Watanabe, S., Kano, R., Sato, H., Nakamura, Y. et al. The effects of Malassezia yeasts on cytokine production by human keratinocytes. J. Invest. Dermatol., 2001, 116, 5, p. 769–773.

51. Wong, A. W., Hon, E. K., Zee, B. Is topical antimycotic treatment useful as adjuvant therapy for flexural atopic dermatitis: randomized, double-blind, controlled trial using one side of the elbow or knee as a control. Int. J. Dermatol., 2008, 47, 2, p. 187–191.

52. Zargari, A., Midgley, G., Back, O., Johansson, S. G. et al. IgE-reactivity to seven Malassezia species. Allergy, 2003, 58, 4, p. 306–311.

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