Serrated adenomas and carcinomas of the colon
Authors:
Alena Chlumská 1,2; Petr Martínek 2; Petr Mukenšnabl 1; Michael Michal 1,2; Michal Zámečník 3,4
Authors‘ workplace:
Šiklův ústav patologie FN, Univerzita Karlova v Plzni, Česká republika
1; Bioptická laboratoř s. r. o., Plzeň, Česká Republika
2; Agel a. s., Laboratoř patologie, Nový Jičín, Česká republika
3; Medirex Group Academy n. o., Bratislava, Slovenská republika
4
Published in:
Čes.-slov. Patol., 52, 2016, No. 1, p. 11-14
Category:
Reviews Article
Overview
Approximately 5 – 35 % of colorectal carcinomas arise through serrated carcinogenesis. The precursor of such carcinomas are serrated adenomas, which differ from conventional adenomas morphologically as well as genetically. Herein, we provide a basic overview of serrated lesions of the large intestine with the focus on histological diagnosis and molecular biology.
Keywords:
hyperplastic polyp – sessile serrated adenoma – traditional serrated adenoma – serrated carcinoma – serrated carcinogenesis
Sources
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Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Czecho-Slovak Pathology
2016 Issue 1
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