Authors: M. Zámečník 1,2 Authors‘ workplace: Šikl’s Department of Pathology, Faculty Hospital, Charles University, Pilsen, Czech Republic 2Department of Pathology, Slovak Postgraduate Academy of Medicine, Derer’s Faculty Hospital, Bratislava, Slovak Republic 1 Published in: Čes.-slov. Patol., , 2002, No. 3, p. 121-124 Category:
An unusual calcifying tumor of the ovary occurring in a 23-year-old woman is described. Thetumor did not produce any endocrine symptoms. Histologically, it was paucicellular and displayedextensive sclerotic stroma with numerous calcifications. The fibroblast-like cells were arrangedin vague pseudolobules thus resembling overall the architecture of the sclerosing stromal tumor(SST), but the hemangiopericytoma-like vasculature typical of SST was not seen. However, immunohistochemicalendothelial markers CD31 and CD34 showed a surprisingly high number of smallvessels that were not apparent in hematoxylin-eosin stained sections. The tumor cells were positivefor alpha-inhibin, CD99, actin, and negative for desmin, S100 protein, and epitehelial markers.This type of ovarian stromal tumor may represent a calcifying stage of SST.
Key words: ovary - sclerosing stromal tumor - calcification - calcifying stromal tumor - inhibin
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