Authors: M. Zámečník 1,2; P. Sedláček 1; M. Gogora 1; P. Mukenšnabl 3 Authors‘ workplace: Oddelenie patológie NsP, Trenčín, primár MUDr. M. Gogora, CSc. 2 Katedra patológie IVZ, Bratislava, vedúci katedry prof. MUDr. I. Slugeň, DrSc. 3 Šiklův ústav patologie FN, Plzeň, prednosta prof. MUDr. F. Fakan, CSc. 1 Published in: Čes.-slov. Patol., , 1999, No. 1, p. 20-23 Category:
An unusual testicular tumour with features of both sex cord tumour with annular tubules andlarge-cell calcifying Sertoli cell tumour is described. The tumour occurred in a 20-year-old man inthe left testis as a 1 cm-measuring well circumscribed solitary lesion. Histologically, it showedsertoliform annular tubules with included eosinophilic nodules as well as isolated large cells andcords to sheets of the cells lying in a sclerosing stroma. A few psammomatous microcalcificationswere seen. In contrast to similar cases reported before, the patient did not have any signs ofPeutz-Jeghers syndrome, feminization or other complex dysplastic syndromes. The case indicatesthat tumours of this type may occur in phenotypically normal patients like pure large cell calcify-ing Sertoli cell tumours or ovarian sex-cord tumours with annular tubules. It further supportsa close histogenetic relationship between these two entities.
Key words: large-cell calcifying Sertoli cell tumour - Peutz-Jeghers syndrome - Sertoli cell tumour - sex - cord tumour with annular tubules - testis
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