Disseminated intravascular coagulation in children

Czech version

Authors: Mazánek Pavel; Blatný Jan
Authors‘ workplace: Oddělení dětské hematologie a biochemie, Lékařská fakulta Masarykovy univerzity a Fakultní nemocnice Brno
Published in: Čes-slov Pediat 2022; 77 (5): 306-309.
Category: Chapters for Specialization in Pediatrics
doi: https://doi.org/10.55095/CSPediatrie2022/050

Overview

Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by excessive systemic activation of coagulation, resulting in both hemorrhage and thrombosis. DIC can progress rapidly into life-threatening multiorgan failure. The diagnosis of overt DIC is based upon a combination of clinical findings and abnormal coagulation studies. The most important principle in managing a child with DIC is to identify and treat the underlying cause. DIC supportive therapy is focused on replacement of consumpted platelets and clotting factors.

Keywords:

bleeding – consumptive coagulopathy – disseminated intravascular coagulation – trombocytopenia – microtrombotization – multi organ failure

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