Perinatal outcome of SARS-CoV-2 infection in pregnancy
Authors:
Korček Peter 1,2; Urbancová Hana 3; Hadravská Šárka 4,5; Straňák Zbyněk 1,2
Authors‘ workplace:
Ústav pro péči o matku a dítě – neonatologie, Praha
1; 3. lékařská fakulta Univerzity Karlovy
2; Ústav pro péči o matku a dítě – klinická patologie, Praha
3; Bioptická laboratoř s. r. o., Plzeň
4; Šiklův ústav patologie, Fakultní nemocnice Plzeň
5
Published in:
Čes-slov Pediat 2022; 77 (1): 27-33.
Category:
Original Papers
Overview
SARS-CoV-2 placentitis is a rare and serious complication of COVID-19 disease in pregnancy. The coronavirus placental infection may lead to maternal and fetal vascular malperfusion (pregnancy itself is a prothrombotic state), fetal demise, intrauterine hypoxia, fetal growth restriction, or preterm birth with the accompanying neonatal morbidity. In case of transplacental transmission of SARS-CoV-2, newborns can also suffer from early-onset viral pneumonia. Consequently, comprehensive epidemiology control should be implemented during pregnancy (frequent testing, contact tracing, vaccination). Furthermore, anticoagulation prophylaxis (low-molecular-weight heparin) and thorough fetal surveillance may be employed in COVID-positive pregnancies, especially in highrisk cases with preexisting placental insufficiency.
Keywords:
Placenta – SARS-CoV-2 – COVID-19 – perinatology – perinatal morbidity
Sources
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Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2022 Issue 1
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