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Current options for assessment of platelet function in neonates


Authors: Z. Straňák 1,2
Authors‘ workplace: Ústav pro péči o matku a dítě, Praha 1;  3. lékařská fakulta UK, Praha 2
Published in: Čes-slov Pediat 2017; 72 (8): 454-456.

Souborný referát věnovaný profesoru Ottovi Hrodkovi, zakladateli výzkumu poruch hemostázy u novorozenců

Overview

Hemostasis is a dynamic process that begins in the fetus within intrauterine development. Blood platelets plays an important part of hemostasis.

Functional and morphological changes of neonatal platelets are presented in this review article as well the historical contribution of Professor Otto Hrodka in the diagnosis of neonatal hemostasis disorders Futhermore current possibilities in the diagnosis of platelet dysfunction in the neonatal period are expressed (evaluation of neonatal platelet aggregation, flow cytometry, agregometry, thrombelastography and rotational thrombelastometry).

Key words:
neonatal platelets, hemostasis disorders, current diagnostic methods


Sources

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10. Hanmod SS, Jesudas R, Kulkarni R, Chitlur M. Neonatal hemostatic disorders: Issues and challenges. Semin Thromb Hemost 2016 Oct; 42 (7): 741–751.

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Labels
Neonatology Paediatrics General practitioner for children and adolescents
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