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Occurrence of Metabolic Syndrome and Its Components in Obese Children


Authors: E. Vitáriušová;  Ľ. Košťálová;  Z. Pribilincová;  A. Hlavatá;  L. Kovács
Authors‘ workplace: 2. detská klinika Lekárskej fakulty Univerzity Komenského a Detskej fakultnej nemocnice s poliklinikou, Bratislava prednosta prof. MUDr. L. Kovács, DrSc., MPH
Published in: Čes-slov Pediat 2010; 65 (2): 55-61.
Category: Original Papers

Overview

Following an increasing prevalence of exogenous obesity in children there is an evidence of more frequent changes in their lipid and glucose metabolism, mediated by insulin resistance. These metabolic changes together with obesity and arterial hypertension are a part of metabolic syndrome.

The aim of study was to evaluate the incidence of obesity complications in childhood in different age groups and prevalence of metabolic syndrome according to the latest partially modified criteria in studied group. In children less than 10 years old there were lower levels of HOMA index and no impaired glucose tolerance found, but 38.1% of probands suffered from hypercholesterolemia. In the group of patients aged 10 to 16 years there was insulin resistance present in 37.7%, increased levels of triglycerides (53.3%), low HDL cholesterol levels (54.4%) and almost in 8% impaired glucose tolerance appeared in this elder age group. Based on modified IDF criteria we have diagnosed metabolic syndrome in 32.5% of studied group patients, while using percentile borderline criteria for blood pressure the percentage of metabolic syndrome increased to 39%. Therapy of referred pathological states requires lifestyle changes and follow-up at the specialized clinic.

Key words:
obesity, childhood, complications, metabolic syndrome


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Labels
Neonatology Paediatrics General practitioner for children and adolescents
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