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Czech Atherosclerosis Society Guidelines for the Diagnosis and Treatment of Dyslipidemias in Children


Authors: Z. Urbanová 1;  M. Šamánek 2;  R. Češka 4;  T. Freiberger 3;  R. Poledne 5;  R. Cífková 6;  H. Vaverková 7;  H. Rosolová 8;  V. Soška 9;  J. Piťha 5;  T. Štulc 4;  M. Vráblík 4
Authors‘ workplace: Klinika dětského a dorostového lékařství, UK 1. LF a Všeobecná fakultní nemocnice, Praha 1;  Dětské kardiocentrum Fakultní nemocnice Motol, Praha 2;  Genetická laboratoř, Centrum kardiovaskulární a transplantační chirurgie, Brno 3;  III. interní klinika, UK 1. LF a Všeobecná fakultní nemocnice, Praha 4;  Laboratoř pro výzkum aterosklerózy, Institut klinické a experimentální medicíny, Praha 5;  Pracoviště preventivní kardiologie, Institut klinické a experimentální medicíny, Praha 6;  III. interní klinika, Lékařská fakulta Univerzity Palackého a Fakultní nemocnice, Olomouc 7;  II. interní klinika, Centrum preventivní kardiologie, UK LF, Plzeň 8;  Oddělení klinické biochemie, Fakultní nemocnice U sv. Anny, Brno 9
Published in: Čes-slov Pediat 2008; 63 (3): 164-172.
Category: Opinion of expert / working groups

Overview

The following recommendation continues the recommendations for diagnostics and therapy of hyperlipoproteinemias in childhood in the Czech Society for Atherosclerosis from 1998 and reflects the changes in evolution of incidence of dyslipidemia and other risk factors of ischemic heart disease at the child population, such as obesity, hypertension, diabetes mellitus, insulin resistance and smoking. It also continues the recommendations of the American Heart Association, published recently in 2007. The recommendations contribute to practical strategy for prevention of atherosclerosis in childhood, performed particularly by physicians engaged in the care of children and adolescents and children cardiologists.

One of the main tasks of pediatricians is to preventively influence the child population as a whole, but especially to disclose children at a high risk of premature atherosclerosis, i.e. namely children with familial hypercholesterolemia and familial defect of lipoprotein B-100 and to apply adequate therapy. The recommendation gives proper attention to most recent knowledge in the area of pathophysiology of dyslipidemias and experience from novel therapeutic procedures in children. The recommendation includes table with practical guide for everyday practice aimed at values which should be reached and remedies to be applied.

Key words:
dyslipidemia, recommendations, children, cardiovascular diseases, prevention


Sources

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2. American Academy of Pediatrics – Committee on Nutrition. Statement on Cholesterol. Pediatrics 1992;90: 469–473.

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5. Kavey RW, Stephen RD, Lauer MR, et al. American Heart Association Guidelines for Primary Prevention of Atherosclerotic Cardiovascular Disease Beginning in Childhood. Circulation 2003;107: 1562–1566.

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7. McCrindle BW, Urbina EM, Dennison BA, et al. Drug therapy of high-risk lipid abnormalities in children and adolescents: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee, Council of Cardiovascular Disease in the Young, with the Council on Cardiovascular Nursing. Circulation 2007;115: 1948–1967.

8. Urbanová Z, Šamánek M, Češka R, et al. Doporučení pro diagnostiku a léčbu hyperlipoproteinémií v dětství a dospívání vypracované výborem České společnosti pro aterosklerózu. Čas. Lék. čes. 1998;137: 89–92.

9. US Preventive Services Task Force. Screening for lipid disorders in children: US Preventive Services Task Force Recommendation Statement. Pediatrics 2007;120: 215–219.

10. Vaverková H, Soška V, Rosolová H, et al. Doporučení pro dignostiku a léčbu dyslipidémií v dospělosti, vypracované výborem České společnosti pro aterosklerózu. Cor Vasa 2007;49: K73–86.

Labels
Neonatology Paediatrics General practitioner for children and adolescents
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